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How to get fromDes Moines to Maryvilleby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 8 ways to get from Des Moines to Maryville by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Des Moines (DSM) to Mcghee Tyson Airport (TYS)plane plane DSM - TYS
    4h 36m
    $238–1,146

  2. Fly to Nashville, drive

    cheapest
    1. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    2. Drive from Nashville-Airport-BNA to Maryvillecar car
    4h 47m
    $138–621

  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    42h 14m
    $375–554

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    42h 17m
    $518–957

  5. Drive 801.4 mi

    1. Drive from Des Moines to Maryvillecar car 801.4 mi
    15h 13m
    $147–212

  6. Fly to Chattanooga Metropolitan Airport, drive

    1. Fly from Des Moines (DSM) to Chattanooga Metropolitan Airport (CHA)plane plane DSM - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Maryvillecar car
    6h 17m
    $235–1,146

  7. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    4. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    44h 1m
    $549–998

  8. Bus via Indianapolis

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    44h 14m
    $397–644

Des Moines (DSM) to Mcghee Tyson Airport (TYS) flights

Calendar83Weekly Planes
Duration5h 15mAverage Duration
Ticket$206Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Maryville.ExpandLaunch map view
  • Distance: 664.5 mi
  • Duration: 4h 36m

What companies run services between Des Moines, IA, USA and Maryville, TN, USA?

United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Mcghee Tyson Airport (TYS) every 2 hours. Alternatively, you can take a bus from Des Moines to Maryville via Chicago Bus Station, New York, NY, and Knoxville, TN in around 42h 14m.

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