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How to get fromDes Moines to Massachusettsby plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 8 ways to get from Des Moines to Massachusetts by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Boston Logan Airport

    best
    1. Fly from Des Moines (DSM) to Boston Logan Airport (BOS)plane plane DSM - BOS
    3h 32m
    $172–776

  2. Fly to Manchester Airport, bus

    cheapest
    1. Fly from Des Moines (DSM) to Manchester Airport (MHT)plane plane DSM - MHT
    2. Take the bus from Boston Manchester Airport to Bostonbus bus
    7h 17m
    $167–786

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Bostontrain train Lake Shore Limited
    30h 16m
    $605–984

  4. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus
    3. Take the bus from New York Midtown to Bostonbus bus
    33h 33m
    $225–364

  5. Drive  1,296.5 mi

    1. Drive from Des Moines to Bostoncar car 1,296.5 mi
    22h 5m
    $237–342

  6. Fly to Bradley International Airport

    1. Fly from Des Moines (DSM) to Bradley International Airport (BDL)plane plane DSM - BDL
    6h 29m
    $208–989

  7. Fly to Worcester Regional Airport

    1. Fly from Des Moines (DSM) to Worcester Regional Airport (ORH)plane plane DSM - ORH
    8h 20m
    $171–775

  8. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bostontrain train
    31h 27m
    $669–1,092

Des Moines to Massachusetts by bus, foot, and train

Calendar7Weekly Services
Duration30h 16mAverage Duration
Ticket$605Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Massachusetts.ExpandLaunch map view
  • Distance: 1,170.9 mi
  • Duration: 3h 32m

What companies run services between Des Moines, IA, USA and Massachusetts, USA?

Allegiant Air, Southwest Airlines, and three other airlines fly from Des Moines (DSM) to Boston Logan Airport (BOS) every 3 hours. Alternatively, you can take a bus from Des Moines to Boston via Chicago Bus Station and New York Midtown in around 33h 33m.

Airlines
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