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How to get fromDes Moines to Massachusettsby plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 9 ways to get from Des Moines to Massachusetts by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Boston Logan Airport

    best
    1. Fly from Des Moines (DSM) to Boston Logan Airport (BOS)plane plane DSM - BOS
    5h 15m
    $132–576

  2. Fly to Theodore Francis Green State Airport, train

    cheapest
    1. Fly from Des Moines (DSM) to Theodore Francis Green State Airport (PVD)plane plane DSM - PVD
    2. Take the train from TF Green Airport to South Stationtrain train
    7h 33m
    $98–399

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0155S / ...
    2. Take the train from Chicago Union Station to Bostontrain train Lake Shore Limited
    31h 16m
    $615–996

  4. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus
    3. Take the bus from New York Midtown to Bostonbus bus
    34h 2m
    $245–386

  5. Drive  1,296.5 mi

    1. Drive from Des Moines to Bostoncar car 1,296.5 mi
    22h 5m
    $222–321

  6. Fly to Worcester Regional Airport

    1. Fly from Des Moines (DSM) to Worcester Regional Airport (ORH)plane plane DSM - ORH
    8h 41m
    $121–505

  7. Fly to Bradley International Airport, train

    1. Fly from Des Moines (DSM) to Bradley International Airport (BDL)plane plane DSM - BDL
    2. Take the train from Hartford Amtrak Station to Springfieldtrain train
    7h 32m
    $175–747

  8. Fly to Manchester Airport, bus

    1. Fly from Des Moines (DSM) to Manchester Airport (MHT)plane plane DSM - MHT
    2. Take the bus from Boston Manchester Airport to Bostonbus bus
    7h 17m
    $123–508

  9. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bostontrain train
    31h 27m
    $673–1,096

Des Moines to Massachusetts by bus, foot, and train

Calendar7Weekly Services
Duration31h 16mAverage Duration
Ticket$615Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Massachusetts.ExpandLaunch map view
  • Distance: 1,170.9 mi
  • Duration: 5h 15m

What companies run services between Des Moines, IA, USA and Massachusetts, USA?

Delta, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Boston Logan Airport (BOS) hourly. Alternatively, you can take a bus from Des Moines to Boston via Chicago Bus Station and New York Midtown in around 34h 2m.

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