There are 4 ways to get from Des Moines to Mayo Clinic by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Des Moines to Albert Leabus Jefferson Lines 802 / ...
- Take the bus from Albert Lea to Rochesterbus Lta 235
5h 38mDrive 207.6 mi
cheapest- Drive from Des Moines to Mayo Cliniccar 207.6 mi
3h 28m$38–55Fly to Rochester
- Fly from Des Moines (DSM) to Rochester (RST)plane DSM - RST
5h 33m$93–491Fly to Minneapolis–Saint Paul International Airport, bus
- Fly from Des Moines (DSM) to Minneapolis–Saint Paul International Airport (MSP)plane DSM - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
4h 16m$150–623
Des Moines (DSM) to Rochester (RST) flights
Questions & Answers
The cheapest way to get from Des Moines to Mayo Clinic is to drive which costs $35 - $55 and takes 3h 28m.
The fastest way to get from Des Moines to Mayo Clinic is to drive which takes 3h 28m and costs $35 - $55.
No, there is no direct bus from Des Moines to Mayo Clinic. However, there are services departing from Des Moines and arriving at Rochester via Albert Lea. The journey, including transfers, takes approximately 5h 38m.
The distance between Des Moines and Mayo Clinic is 221 miles. The road distance is 208.8 miles.
The best way to get from Des Moines to Mayo Clinic without a car is to bus which takes 5h 38m and costs .
It takes approximately 5h 38m to get from Des Moines to Mayo Clinic, including transfers.
Des Moines to Mayo Clinic bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Des Moines to Mayo Clinic is to bus which takes 5h 38m and costs . Alternatively, you can fly, which costs $90 - $500 and takes 5h 33m.
Des Moines to Mayo Clinic bus services, operated by Jefferson Lines, arrive at Albert Lea station.
Yes, the driving distance between Des Moines to Mayo Clinic is 209 miles. It takes approximately 3h 28m to drive from Des Moines to Mayo Clinic.
What companies run services between Des Moines, IA, USA and Mayo Clinic, MN, USA?
You can take a bus from Des Moines to Mayo Clinic via Albert Lea and Rochester in around 5h 38m. Alternatively, Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Rochester (RST) every 3 hours.
- Website
- delta.com
Flights from Des Moines to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $75–470
Flights from Des Moines to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $80–550
- Website
- aa.com
Flights from Des Moines to Rochester via Chicago O'Hare
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Des Moines to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $100–550
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Albert Lea
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $45–65
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–65
- Website
- example.com
Bus from Albert Lea to Rochester
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Schedules at
- example.com
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
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