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How to get fromDes Moines to Memphisby plane, bus (Greyhound, Flixbus), car, bus, or train

Find Transport to Memphis

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There are 5 ways to get from Des Moines to Memphis by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Memphis (MEM)plane plane DSM - MEM
    6h 11m
    $219–1,122

  2. Drive 596.3 mi

    cheapest
    1. Drive from Des Moines to Memphiscar car 596.3 mi
    10h 54m
    $109–158

  3. Bus via St. Louis

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus FlixBus 2510
    15h 27m
    $111–206

  4. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson 803 / ...
    2. Take the bus from Kansas City to Memphis Bus Stationbus bus Jefferson 121
    15h 57m
    $164–234

  5. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    17h 56m
    $189–349

Des Moines to Memphis by bus

Calendar7Weekly Buses
Duration15h 27mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Memphis.ExpandLaunch map view
  • Distance: 510.3 mi
  • Duration: 6h 11m

What companies run services between Des Moines, IA, USA and Memphis, TN, USA?

Delta, American Airlines, and two other airlines fly from Des Moines (DSM) to Memphis (MEM) hourly. Alternatively, you can take a bus from Des Moines to 3RD STREET at EXCHANGE AVENUE via St Louis Bus Station and Airways Transit Center in around 15h 27m.

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