Rome2Rio

How to get fromDes Moines to Memphisby plane, bus (Greyhound, Flixbus), car, bus (Greyhound, Amtrak, Flixbus), bus, or train

Find Transport to Memphis

See all options

There are 6 ways to get from Des Moines to Memphis by plane, bus (Greyhound, Flixbus), car, bus (Greyhound, Amtrak, Flixbus), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Memphis (MEM)plane plane DSM - MEM
    5h 59m
    $189–922

  2. Drive  596.3 mi

    cheapest
    1. Drive from Des Moines to Memphiscar car 596.3 mi
    10h 54m
    $109–158

  3. Bus via Kansas City

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    16h 27m
    $129–223

  4. Bus

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the bus from Springfield SMTD Transfer Center to Memphis Bus Stationbus bus
    17h 23m
    $117–198

  5. Bus, train

    1. Take the bus from Des Moines to Bloomington-Normalbus bus
    2. Take the train from Bloomington-Normal to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    18h 2m
    $122–253

  6. Bus, train via Kansas City

    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    18h 42m
    $139–303

Des Moines to Memphis by bus

Calendar12Weekly Buses
Duration16h 27mAverage Duration
Ticket$129Cheapest Price
See schedules

Questions & Answers

Map of how to get from Des Moines to Memphis.ExpandLaunch map view
  • Distance: 510.3 mi
  • Duration: 5h 59m

What companies run services between Des Moines, IA, USA and Memphis, TN, USA?

Delta, United Airlines, and two other airlines fly from Des Moines (DSM) to Memphis (MEM) hourly. Alternatively, you can take a bus from Des Moines to 3RD STREET at EXCHANGE AVENUE via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Airways Transit Center in around 16h 27m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers