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How to get fromDes Moines to Mendotaby bus, train, car, or plane

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There are 4 ways to get from Des Moines to Mendota by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Des Moines to Galesburgbus bus Greyhound US0157S
    2. Take the train from Galesburg Amtrak Station to Mendota Stationtrain train Southwest Chief / ...
    6h 43m
    $56–114

  2. Drive 241.7 mi

    cheapest
    1. Drive from Des Moines to Mendotacar car 241.7 mi
    4h 32m
    $45–64

  3. Fly to Chicago Midway International Airport, train

    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2. Take the train from Chicago Union Station to Mendota Stationtrain train
    4h 51m
    $119–534

  4. Fly to Chicago O'Hare International Airport, train

    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2. Take the train from Chicago Union Station to Mendota Stationtrain train
    5h 9m
    $106–461

Des Moines to Mendota by bus and train

Calendar7Weekly Services
Duration6h 43mAverage Duration
Ticket$56Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Mendota.ExpandLaunch map view
  • Distance: 285.7 mi
  • Duration: 6h 43m

What companies run services between Des Moines, IA, USA and Mendota, IL, USA?

There is no direct connection from Des Moines to Mendota. However, you can take the bus to Galesburg, walk to Galesburg Amtrak Station, then take the train to Mendota Station. Alternatively, you can drive from Des Moines to Mendota in around 4h 32m.

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