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How to get fromDes Moines to Meridianby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Flixbus)

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There are 9 ways to get from Des Moines to Meridian by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Meridian

    best
    1. Fly from Des Moines (DSM) to Meridian (MEI)plane plane DSM - MEI
    5h 41m
    $184–792

  2. Drive  823 mi

    cheapest
    1. Drive from Des Moines to Meridiancar car 823 mi
    15h 34m
    $151–217

  3. Bus

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the bus from Champaign Intermodal Trans Ctr to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Meridian Bus Stopbus bus
    22h
    $161–252

  4. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Jacksontrain train
    3. Take the bus from Jackson to Meridian Bus Stopbus bus
    23h 30m
    $411–661

  5. Fly to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Des Moines (DSM) to Birmingham–Shuttlesworth International Airport (BHM)plane plane DSM - BHM
    2. Drive from Birmingham-Airport-BHM to Meridiancar car
    6h 38m
    $246–1,163

  6. Fly to Hattiesburg–Laurel Regional Airport, drive

    1. Fly from Des Moines (DSM) to Hattiesburg–Laurel Regional Airport (PIB)plane plane DSM - PIB
    2. Drive from Hattiesburg–Laurel Regional Airport (PIB) to Meridiancar car
    9h 35m
    $183–794

  7. Fly to Golden Triangle Regional Airport, drive

    1. Fly from Des Moines (DSM) to Golden Triangle Regional Airport (GTR)plane plane DSM - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Meridiancar car
    7h 51m
    $165–747

  8. Fly to Jackson/Vicksburg, bus

    1. Fly from Des Moines (DSM) to Jackson/Vicksburg (JAN)plane plane DSM - JAN
    2. Take the bus from Jackson to Meridian Bus Stopbus bus
    7h 39m
    $204–797

  9. Bus via Tulsa

    1. Take the bus from Des Moines to Tulsabus bus
    2. Take the bus from Tulsa to Memphisbus bus
    3. Take the bus from Memphis Bus Station to Meridian Bus Stopbus bus
    25h 25m
    $239–348

Des Moines to Meridian by bus

Calendar5Weekly Buses
Duration22hAverage Duration
Ticket$161Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Meridian.ExpandLaunch map view
  • Distance: 701.4 mi
  • Duration: 5h 41m

What companies run services between Des Moines, IA, USA and Meridian, MS, USA?

United Airlines flies from Des Moines (DSM) to Meridian (MEI) 4 times a day. Alternatively, you can take a bus from Des Moines to Meridian Bus Stop via Champaign Intermodal Trans Ctr and Memphis Bus Station in around 22h.

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