Rome2Rio

How to get fromDes Moines to Mesaby plane, bus, train, car, or bus (Greyhound)

Find Transport to Mesa

See all options

There are 6 ways to get from Des Moines to Mesa by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Phoenix

    best
    1. Fly from Des Moines (DSM) to Phoenix (PHX)plane plane DSM - PHX
    4h 10m
    $140–623

  2. Bus via Ciudad Juárez

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from 2745 Southwest Blvd - Kansas City to El Pasobus bus
    3. Take the bus from El Paso to Phoenixbus bus
    33h 21m
    $255–359

  3. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to Flagstafftrain train
    3. Take the bus from Flagstaff Train Station to Tempebus bus
    33h 23m
    $416–909

  4. Drive 1,380.2 mi

    1. Drive from Des Moines to Mesacar car 1,380.2 mi
    24h 4m
    $252–364

  5. Fly to Phoenix-Mesa Gateway Airport

    1. Fly from Des Moines (DSM) to Phoenix-Mesa Gateway Airport (AZA)plane plane DSM - AZA
    5h 10m
    $154–677

  6. Bus

    1. Take the bus from Des Moines to Tulsabus bus Jefferson Lines 801
    2. Take the bus from Tulsa Bus Station to Phoenix Bus Stationbus bus Greyhound US1210
    36h 47m
    $268–448

Des Moines to Mesa by bus, foot, and tram

Calendar7Weekly Services
Duration33h 21mAverage Duration
Ticket$255Cheapest Price
See schedules

Questions & Answers

Map of how to get from Des Moines to Mesa.ExpandLaunch map view
  • Distance: 1,167.3 mi
  • Duration: 4h 10m

What companies run services between Des Moines, IA, USA and Mesa, AZ, USA?

American Airlines, Southwest Airlines, and United Airlines fly from Des Moines (DSM) to Phoenix (PHX) every 3 hours. Alternatively, you can take a bus from Des Moines to Mesa Dr/Main St via Kansas City, On 12Th At Troost Westbound Farside, On Southwest Blvd At 27Th St Southbound, 2745 Southwest Blvd - Kansas City, El Paso, El Paso, Phoenix, and 24th St/Jefferson in around 33h 21m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers