There are 6 ways to get from Des Moines to Mexico by bus, taxi, car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, taxi
best- Take the bus from Des Moines to Kansas City Bus Stationbus
- Take the bus from Kansas City Bus Station to Columbiabus
- Take the taxi from Columbia to Mexicotaxi
7h 19m$198–285Drive 229.8 mi
cheapest- Drive from Des Moines to Mexicocar 229.8 mi
4h 55m$42–61Fly to Columbia Regional Airport, taxi
- Fly from Des Moines (DSM) to Columbia Regional Airport (COU)plane DSM - COU
- Take the taxi from Columbia Regional Airport (COU) to Mexicotaxi
5h 12m$288–831Bus, drive (Greyhound)
- Take the bus from Des Moines to Quincy Public Transit Hubbus Greyhound US0153S
- Drive from Quincy Public Transit Hub to Mexicocar
7h 21m$56–100Bus, taxi via Des Moines
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to Columbiabus
- Take the taxi from Columbia to Mexicotaxi
7h 34m$222–302Fly to Lambert–St. Louis International Airport, shuttle
- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
- Take a shuttle bus from St. Louis to Bowling Green, Mo
- Take a shuttle bus from Bowling Green, Mo to Mexico, MO
8h 7m$184–856
Des Moines (DSM) to Columbia Regional Airport (COU) flights
Questions & Answers
The cheapest way to get from Des Moines to Mexico is to drive which costs $40 - $65 and takes 4h 55m.
The fastest way to get from Des Moines to Mexico is to drive which takes 4h 55m and costs $40 - $65.
The distance between Des Moines and Mexico is 361 miles. The road distance is 231.1 miles.
The best way to get from Des Moines to Mexico without a car is to bus and taxi which takes 7h 19m and costs $190 - $290.
It takes approximately 7h 19m to get from Des Moines to Mexico, including transfers.
Yes, the driving distance between Des Moines to Mexico is 231 miles. It takes approximately 4h 55m to drive from Des Moines to Mexico.
There are three+ hotels available in Mexico.
What companies run services between Des Moines, IA, USA and Mexico, MO, USA?
There is no direct connection from Des Moines to Mexico. However, you can take the bus to Kansas City Bus Station, take the bus to Columbia, then take the taxi to Mexico. Alternatively, you can drive from Des Moines to Mexico in around 4h 55m.
- Website
- aa.com
Flights from Des Moines to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $100–600
Flights from Des Moines to Columbia Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to Columbia Regional Airport via Charlotte
- Ave. Duration
- 8h 36m
- When
- Sunday
- Estimated price
- $190–850
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $230–1,100
- Website
- united.com
Flights from Des Moines to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $100–600
Flights from Des Moines to Columbia Regional Airport via Denver
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $170–800
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $260–1,200
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 56m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $260–1,200
- Website
- delta.com
Flights from Des Moines to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $160–850
Flights from Des Moines to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Des Moines to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $200–950
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Kansas City Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- Greyhound
Bus from Kansas City Bus Station to Columbia
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a day
- Estimated price
- $19–40
- Website
- Greyhound
Bus from Des Moines to Quincy Public Transit Hub
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $40–80
- Website
- Greyhound
Bus from Kansas City Bus Station to Columbia
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a day
- Estimated price
- $19–40
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
- Phone
- +1-888-875-6287
- Website
- Oats Transit
Shuttle from St. Louis to Bowling Green, Mo
- Ave. Duration
- 1h 15m
- Frequency
- Twice a week
- Estimated price
- $3–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
Shuttle from Bowling Green, Mo to Mexico, MO
- Ave. Duration
- 58 min
- Frequency
- On demand
- Estimated price
- $3–5
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
- Ave. Duration
- 48 min
- Estimated price
- $150–210
Taxi Terry's
- Phone
- +1-573-441-1414
- Website
- taxicolumbiamo.com
Taxi Terry's
- Phone
- +1-573-441-1414
- Website
- taxicolumbiamo.com
Checker Cab
- Phone
- +1-573-636-7101
Taxi Terry's
- Phone
- +1-573-441-1414
- Website
- taxicolumbiamo.com
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