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How to get fromDes Moines to Natchezby plane, bus, train, car, or taxi

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There are 8 ways to get from Des Moines to Natchez by plane, bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Natchez

    best
    1. Fly from Des Moines (DSM) to Natchez (HEZ)plane plane DSM - HEZ
    7h 24m
    $166–656

  2. Fly to Baton Rouge Metropolitan Airport, drive

    cheapest
    1. Fly from Des Moines (DSM) to Baton Rouge Metropolitan Airport (BTR)plane plane DSM - BTR
    2. Drive from Baton-Rouge-Airport-BTR to Natchezcar car
    6h 36m
    $143–644

  3. Bus, train, drive

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Brookhaven Stationtrain train
    3. Drive from Brookhaven Station to Natchezcar car
    23h 28m
    $246–522

  4. Bus, train, drive via Kansas City

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Jacksonbus bus
    4. Take the train from Jackson to Brookhaven Stationtrain train
    5. Drive from Brookhaven Station to Natchezcar car
    24h 24m
    $193–364

  5. Drive  801.6 mi

    1. Drive from Des Moines to Natchezcar car 801.6 mi
    15h 52m
    $147–212

  6. Fly to Alexandria International Airport, taxi

    1. Fly from Des Moines (DSM) to Alexandria International Airport (AEX)plane plane DSM - AEX
    2. Take the taxi from Alexandria International Airport (AEX) to Natcheztaxi taxi
    6h 20m
    $150–597

  7. Fly to Monroe Regional Airport, taxi

    1. Fly from Des Moines (DSM) to Monroe Regional Airport (MLU)plane plane DSM - MLU
    2. Take the taxi from Monroe Regional Airport (MLU) to Natcheztaxi taxi
    6h 34m
    $150–597

  8. Fly to Lafayette Regional Airport, taxi

    1. Fly from Des Moines (DSM) to Lafayette Regional Airport (LFT)plane plane DSM - LFT
    2. Take the taxi from Lafayette Regional Airport (LFT) to Natcheztaxi taxi
    7h 54m
    $150–647

Des Moines (DSM) to Natchez (HEZ) flights

Calendar13Weekly Planes
Duration6h 55mAverage Duration
Ticket$123Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Natchez.ExpandLaunch map view
  • Distance: 714.4 mi
  • Duration: 7h 24m

What companies run services between Des Moines, IA, USA and Natchez, MS, USA?

United Airlines flies from Des Moines (DSM) to Natchez (HEZ) twice daily.

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