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How to get fromDes Moines to Niagara Fallsby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

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There are 9 ways to get from Des Moines to Niagara Falls by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Des Moines (DSM) to Buffalo Niagara International Airport (BUF)plane plane DSM - BUF
    6h 30m
    $161–776

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    20h 33m
    $97–231

  3. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    21h 49m
    $218–610

  4. Drive 831.5 mi

    1. Drive from Des Moines to Niagara Fallscar car 831.5 mi
    14h 6m
    $152–220

  5. Fly to Toronto Island Airport, bus

    1. Fly from Des Moines (DSM) to Toronto Island Airport (YTZ)plane plane DSM - YTZ
    2. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    8h 10m
    $110–536

  6. Fly to Toronto Pearson International Airport, bus

    1. Fly from Des Moines (DSM) to Toronto Pearson International Airport (YYZ)plane plane DSM - YYZ
    2. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    7h 29m
    $116–535

  7. Fly to Rochester, train

    1. Fly from Des Moines (DSM) to Rochester (ROC)plane plane DSM - ROC
    2. Take the train from Rochester to Niagara Falls Amtrak Stationtrain train
    7h 34m
    $241–1,163

  8. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    22h 5m
    $193–405

  9. Bus via Detroit

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Union Station to Detroitbus bus
    3. Take the bus from Detroit Bus Station to Torontobus bus
    4. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    24h 19m
    $170–331

Des Moines to Niagara Falls by bus

Calendar7Weekly Buses
Duration20h 33mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Niagara Falls.ExpandLaunch map view
  • Distance: 809.7 mi
  • Duration: 6h 30m

What companies run services between Des Moines, IA, USA and Niagara Falls, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Des Moines to Main Street & Pine Avenue via Chicago, Cleveland, OH, and Ellicott Street & MTC Static in around 20h 33m.

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