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How to get fromDes Moines to North Carolinaby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 11 ways to get from Des Moines to North Carolina by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charlotte Douglas International Airport

    best
    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    3h 16m
    $211–974

  2. Fly to Fayetteville Municipal Airport

    cheapest
    1. Fly from Des Moines (DSM) to Fayetteville Municipal Airport (FAY)plane plane DSM - FAY
    4h 46m
    $174–740

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charlottebus bus
    25h 15m

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    36h 9m

  5. Drive 1,029.4 mi

    1. Drive from Des Moines to Charlottecar car 1,029.4 mi
    17h 40m
    $188–272

  6. Fly to Piedmont Triad International Airport

    1. Fly from Des Moines (DSM) to Piedmont Triad International Airport (GSO)plane plane DSM - GSO
    4h 45m
    $276–1,156

  7. Fly to Wilmington International Airport

    1. Fly from Des Moines (DSM) to Wilmington International Airport (ILM)plane plane DSM - ILM
    4h 32m
    $182–788

  8. Fly to Raleigh-Durham International Airport

    1. Fly from Des Moines (DSM) to Raleigh-Durham International Airport (RDU)plane plane DSM - RDU
    5h 45m
    $181–824

  9. Bus via Columbus

    1. Take the bus from Des Moines to Indianapolisbus bus
    2. Take the bus from Indianapolis Union Station to Wilson & Ferrell Shell Station - Columbusbus bus
    3. Take the bus from Columbus to Charlottebus bus
    25h 44m

  10. Bus, train via Ironville

    1. Take the bus from Des Moines to Indianapolisbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland to Wythevillebus bus
    4. Take the bus from Wytheville to Charlotte Bus Stationbus bus
    25h 55m

  11. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain train
    38h

Des Moines (DSM) to Charlotte Douglas International Airport (CLT) flights

Calendar74Weekly Planes
Duration4h 14mAverage Duration
Ticket$196Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to North Carolina.ExpandLaunch map view
  • Distance: 827.8 mi
  • Duration: 3h 16m

What companies run services between Des Moines, IA, USA and North Carolina, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT) every 2 hours. Alternatively, you can take a bus from Des Moines to Charlotte via St Louis Bus Station and Atlanta Bus Station in around 25h 15m.

Airlines
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