There are 3 ways to get from Des Moines to O'Fallon by bus (Greyhound), car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Des Moines to St Louis Bus Stationbus Greyhound US0153S
9h 57m$70–128Drive 345.7 mi
cheapest- Drive from Des Moines to O'Falloncar 345.7 mi
6h 58m$64–92Fly, train
- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
- Take the train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT stationtrain
6h 6m$162–825
Des Moines to O'Fallon by bus and train (Greyhound)
Questions & Answers
The cheapest way to get from Des Moines to O'Fallon is to drive which costs $60 - $95 and takes 6h 58m.
The fastest way to get from Des Moines to O'Fallon is to fly and train which takes 6h 6m and costs $160 - $850.
No, there is no direct bus from Des Moines to O'Fallon. However, there are services departing from Des Moines and arriving at State @ Lincoln Eb via Fairview Heights Transit Center. The journey, including transfers, takes approximately 9h 57m.
The distance between Des Moines and O'Fallon is 441 miles. The road distance is 347.7 miles.
The best way to get from Des Moines to O'Fallon without a car is to bus which takes 9h 57m and costs $70 - $130.
It takes approximately 9h 57m to get from Des Moines to O'Fallon, including transfers.
Des Moines to O'Fallon bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to O'Fallon bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Des Moines to O'Fallon is 348 miles. It takes approximately 6h 58m to drive from Des Moines to O'Fallon.
There are 76+ hotels available in O'Fallon.
What companies run services between Des Moines, IA, USA and O'Fallon, IL, USA?
Greyhound USA operates a bus from Des Moines to St Louis Bus Station once daily. Tickets cost $65–130 and the journey takes 8h 20m.
- Website
- aa.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $240–1,100
- Website
- united.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $270–1,200
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $150–800
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 56m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $270–1,200
- Website
- delta.com
Flights from Des Moines to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $160–850
Flights from Des Moines to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $250–1,200
Flights from Des Moines to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $210–1,000
- Phone
- 314-982-1406
- [email protected]
- Website
- metrostlouis.org
Train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT station
- Ave. Duration
- 1h 14m
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- https://www.metrostlouis.org
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
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