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How to get fromDes Moines to Orlandoby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 5 ways to get from Des Moines to Orlando by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Orlando

    best
    1. Fly from Des Moines (DSM) to Orlando (MCO)plane plane DSM - MCO
    5h 24m
    $180–773
  2. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Orlando Bus Stationbus bus
    29h 40m
    $222–434
  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Orlandotrain train Floridian
    46h 39m
    $604–1,300
  4. Drive 1,305.3 mi

    1. Drive from Des Moines to Orlandocar car 1,305.3 mi
    23h 18m
    $239–345
  5. Fly to Orlando Sanford

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    3h 37m
    $238–846

Des Moines to Orlando by bus

Calendar7Weekly Buses
Duration29h 40mAverage Duration
Ticket$222Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Orlando, FL, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Orlando (MCO) every 2 hours. Alternatively, you can take a bus from Des Moines to Orlando Bus Station via St Louis Bus Station and Atlanta Bus Station in around 29h 40m.

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