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How to get fromDes Moines to Orlandoby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 5 ways to get from Des Moines to Orlando by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Orlando

    best
    1. Fly from Des Moines (DSM) to Orlando (MCO)plane plane DSM - MCO
    5h 24m
    $150–673
  2. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Orlando Bus Stationbus bus
    30h 50m
    $200–393
  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Orlandotrain train Floridian
    46h 39m
    $497–1,089
  4. Drive  1,305.3 mi

    1. Drive from Des Moines to Orlandocar car 1,305.3 mi
    23h 18m
    $239–345
  5. Fly to Orlando Sanford

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    3h 31m
    $198–696

Des Moines to Orlando by bus

Calendar7Weekly Buses
Duration30h 50mAverage Duration
Ticket$200Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Orlando, FL, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Orlando (MCO) hourly. Alternatively, you can take a bus from Des Moines to Orlando Bus Station via Indianapolis Union Station and Atlanta Bus Station in around 30h 50m.

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