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How to get fromDes Moines to Paducahby plane, bus (Greyhound, Flixbus), car, or bus

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There are 6 ways to get from Des Moines to Paducah by plane, bus (Greyhound, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Barkley Regional Airport

    best
    1. Fly from Des Moines (DSM) to Barkley Regional Airport (PAH)plane plane DSM - PAH
    5h 44m
    $129–533

  2. Drive 490 mi

    cheapest
    1. Drive from Des Moines to Paducahcar car 490 mi
    9h 59m
    $90–130

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the bus from St Louis Bus Station to Paducah Bus Stationbus bus FlixBus N2521
    12h 34m
    $91–161

  4. Drive to Fort Dodge Municipal Airport, fly to Barkley Regional Airport

    1. Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Barkley Regional Airport (PAH)plane plane FOD - PAH
    20h 41m
    $113–447

  5. Fly Des Moines to Nashville, bus

    1. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    5h 57m
    $132–559

  6. Fly Des Moines to Williamson County Regional Airport, bus

    1. Fly from Des Moines (DSM) to Williamson County Regional Airport (MWA)plane plane DSM - MWA
    2. Take the bus from Carbondale Intermodal Station to Paducah Bus Stationbus bus
    8h 45m
    $152–559

Des Moines (DSM) to Barkley Regional Airport (PAH) flights

Calendar21Weekly Planes
Duration6hAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Paducah.ExpandLaunch map view
  • Distance: 421.6 mi
  • Duration: 5h 44m

What companies run services between Des Moines, IA, USA and Paducah, KY, USA?

United Airlines and American Airlines fly from Des Moines (DSM) to Barkley Regional Airport (PAH) 3 times a day. Alternatively, you can take a bus from Des Moines to Paducah via St Louis Bus Station and Paducah Bus Station in around 12h 34m.

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