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How to get fromDes Moines to Paducahby plane, bus (Greyhound, Flixbus), car, bus, or train

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There are 8 ways to get from Des Moines to Paducah by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Barkley Regional Airport

    best
    1. Fly from Des Moines (DSM) to Barkley Regional Airport (PAH)plane plane DSM - PAH
    5h 50m
    $135–545

  2. Drive  490 mi

    cheapest
    1. Drive from Des Moines to Paducahcar car 490 mi
    9h 59m
    $90–130

  3. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Paducah Bus Stationbus bus
    12h 44m
    $121–188

  4. Drive to Fort Dodge Municipal Airport, fly to Barkley Regional Airport

    1. Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Barkley Regional Airport (PAH)plane plane FOD - PAH
    20h 57m
    $113–447

  5. Fly Des Moines to Williamson County Regional Airport, bus

    1. Fly from Des Moines (DSM) to Williamson County Regional Airport (MWA)plane plane DSM - MWA
    2. Take the bus from Carbondale Intermodal Station to Paducah Bus Stationbus bus
    6h 46m
    $158–640

  6. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Carbondaletrain train
    3. Take the bus from Carbondale Intermodal Station to Paducah Bus Stationbus bus
    13h 38m
    $118–221

  7. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the train from Springfield to St. Louistrain train
    4. Take the bus from St Louis Bus Station to Paducah Bus Stationbus bus
    14h 47m
    $118–202

  8. Bus, train via Kansas City

    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Paducah Bus Stationbus bus
    14h 51m
    $134–259

Des Moines (DSM) to Barkley Regional Airport (PAH) flights

Calendar28Weekly Planes
Duration6h 44mAverage Duration
Ticket$90Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Paducah.ExpandLaunch map view
  • Distance: 421.6 mi
  • Duration: 5h 50m

What companies run services between Des Moines, IA, USA and Paducah, KY, USA?

United Airlines and American Airlines fly from Des Moines (DSM) to Barkley Regional Airport (PAH) 4 times a day. Alternatively, you can take a bus from Des Moines to Paducah via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Paducah Bus Station in around 12h 44m.

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