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How to get fromDes Moines to Palm Beachby plane, train, bus (Greyhound), bus, or car

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There are 7 ways to get from Des Moines to Palm Beach by plane, train, bus (Greyhound), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Fort Lauderdale–Hollywood International Airport, train

    best
    1. Fly from Des Moines (DSM) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane DSM - FLL
    2. Take the train from Fort Lauderdale to West Palm Beachtrain train
    5h 34m
    $203–883

  2. Fly to President Donald J. Trump International Airport

    cheapest
    1. Fly from Des Moines (DSM) to President Donald J. Trump International Airport (PBI)plane plane DSM - PBI
    6h 42m
    $173–777

  3. Bus (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to West Palm Beach Bus Stationbus bus
    38h 33m
    $249–415

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to West Palm Beach Amtrak Stationtrain train Floridian
    2d 5h
    $534–1,283

  5. Drive  1,465.3 mi

    1. Drive from Des Moines to Palm Beachcar car 1,465.3 mi
    25h 52m
    $268–387

  6. Fly to Miami International Airport, train

    1. Fly from Des Moines (DSM) to Miami International Airport (MIA)plane plane DSM - MIA
    2. Take the train from Miami Airport Station to West Palm Beach Stationtrain train
    6h 20m
    $176–736

  7. Fly to Orlando Sanford, drive

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Palm Beachcar car
    6h 5m
    $179–723

Des Moines to Palm Beach by bus (Greyhound)

Calendar7Weekly Buses
Duration38h 33mAverage Duration
Ticket$249Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Palm Beach.ExpandLaunch map view
  • Distance: 1,371.8 mi
  • Duration: 5h 34m

What companies run services between Des Moines, IA, USA and Palm Beach, FL, USA?

You can take a bus from Des Moines to QUADRILLE BLVD at OKEECHOBEE BLVD E via Indianapolis Union Station, Atlanta Bus Station, West Palm Beach Bus Station, and WPB ITC at TRI RAIL in around 38h 33m. Alternatively, Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to President Donald J. Trump International Airport (PBI) every 2 hours.

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