There are 10 ways to get from Des Moines to Pennsylvania by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Philadelphia International Airport
best- Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane DSM - PHL
3h 21m$161–727Fly to Erie International Airport
cheapest- Fly from Des Moines (DSM) to Erie International Airport (ERI)plane DSM - ERI
5h 28m$116–575Bus (Greyhound)
- Take the bus from Des Moines to Indianapolis Union Stationbus Greyhound US0157S
- Take the bus from Indianapolis Union Station to Philadelphia Bus Stationbus Greyhound US0421
27h 15m$172–284Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Rockville Amtraktrain
- Take the train from Washington Union Station to 30th Street Stationtrain
28h 50m$296–663Drive 1,073.5 mi
- Drive from Des Moines to Philadelphiacar 1,073.5 mi
17h 41m$196–283Fly to Wilkes-Barre/Scranton International Airport
- Fly from Des Moines (DSM) to Wilkes-Barre/Scranton International Airport (AVP)plane DSM - AVP
4h 42m$179–723Fly to Pittsburgh International Airport
- Fly from Des Moines (DSM) to Pittsburgh International Airport (PIT)plane DSM - PIT
5h 16m$129–673Fly to Laguardia Airport, train
- Fly from Des Moines (DSM) to Laguardia Airport (LGA)plane DSM - LGA
- Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain
5h 27m$214–1,483Bus via Chicago
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the bus from Chicago Bus Station to Philadelphia Bus Stationbus FlixBus N2642
28h 15m$182–292Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the train from Chicago Union Station to 30th Street Stationtrain Cardinal
34h 15m$324–686
Des Moines to Pennsylvania by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Des Moines to Pennsylvania is to bus which costs $170 - $290 and takes 27h 15m.
The fastest way to get from Des Moines to Pennsylvania is to fly which takes 3h 21m and costs $160 - $750.
No, there is no direct bus from Des Moines to Pennsylvania station. However, there are services departing from Des Moines and arriving at Philadelphia Bus Station via Indianapolis Union Station. The journey, including transfers, takes approximately 27h 15m.
The distance between Des Moines and Pennsylvania is 990 miles. The road distance is 1079.8 miles.
The best way to get from Des Moines to Pennsylvania without a car is to bus which takes 27h 15m and costs $170 - $290.
It takes approximately 3h 21m to get from Des Moines to Pennsylvania, including transfers.
Des Moines to Pennsylvania bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Pennsylvania is to fly which takes 3h 21m and costs $160 - $750. Alternatively, you can bus, which costs $170 - $290 and takes 27h 15m.
Des Moines to Pennsylvania bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Pennsylvania is 1h ahead of Des Moines. It is currently 4:27 PM in Des Moines and 5:27 PM in Pennsylvania.
What companies run services between Des Moines, IA, USA and Pennsylvania, USA?
American Airlines, Allegiant Air, and three other airlines fly from Des Moines (DSM) to Philadelphia International Airport (PHL) every 2 hours. Alternatively, you can take a bus from Des Moines to Philadelphia Bus Station via Indianapolis Union Station in around 27h 15m.
- Website
- aa.com
Flights from Des Moines to Philadelphia International Airport
- Ave. Duration
- 2h 37m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Philadelphia International Airport via Chicago O'Hare
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Wilkes-Barre/Scranton International Airport via Chicago O'Hare
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Wilkes-Barre/Scranton International Airport via Charlotte
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $160–750
Flights from Des Moines to Pittsburgh International Airport via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $110–650
Flights from Des Moines to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to Pittsburgh International Airport via Charlotte
- Ave. Duration
- 5h 44m
- When
- Thursday and Sunday
- Estimated price
- $160–800
Flights from Des Moines to Erie International Airport via Chicago O'Hare
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $95–550
Flights from Des Moines to Erie International Airport via Charlotte
- Ave. Duration
- 7h 59m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Laguardia Airport
- Ave. Duration
- 2h 48m
- When
- Every day
- Estimated price
- $170–850
Flights from Des Moines to Laguardia Airport via Chicago O'Hare
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $170–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $40–95
- Website
- Amtrak
Train from Chicago Union Station to Rockville Amtrak
- Ave. Duration
- 16h 41m
- Frequency
- Once daily
- Estimated price
- $190–430
- Website
- Amtrak
Train from Washington Union Station to 30th Street Station
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $30–80
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 21m
- Frequency
- Every 30 minutes
- Estimated price
- $23–55
- Website
- Amtrak
Train from Chicago Union Station to 30th Street Station
- Ave. Duration
- 25h 56m
- Frequency
- 3 times a week
- Estimated price
- $270–600
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $70–120
- Website
- Greyhound
Bus from Indianapolis Union Station to Philadelphia Bus Station
- Ave. Duration
- 16h 35m
- Frequency
- 3 times a day
- Estimated price
- $100–170
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–85
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–85
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Des Moines to Pennsylvania is 1080 miles. It takes approximately 17h 41m to drive from Des Moines to Pennsylvania.
Book your Des Moines to Pennsylvania bus tickets online with Omio and FlixBus.
There are 917+ hotels available in Pennsylvania.








