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How to get fromDes Moines to Pennsylvaniaby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

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There are 11 ways to get from Des Moines to Pennsylvania by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Philadelphia International Airport

    best
    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane plane DSM - PHL
    3h 41m
    $121–577

  2. Fly to Erie International Airport

    cheapest
    1. Fly from Des Moines (DSM) to Erie International Airport (ERI)plane plane DSM - ERI
    5h 28m
    $91–425

  3. Bus (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Philadelphia Bus Stationbus bus Greyhound US0421
    27h
    $203–302

  4. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Rockville Amtraktrain train
    4. Take the train from Washington Union Station to 30th Street Stationtrain train
    28h 50m
    $606–972

  5. Drive  1,073.5 mi

    1. Drive from Des Moines to Philadelphiacar car 1,073.5 mi
    17h 40m
    $184–265

  6. Fly to Wilkes-Barre/Scranton International Airport

    1. Fly from Des Moines (DSM) to Wilkes-Barre/Scranton International Airport (AVP)plane plane DSM - AVP
    5h 1m
    $139–508

  7. Fly to Pittsburgh International Airport

    1. Fly from Des Moines (DSM) to Pittsburgh International Airport (PIT)plane plane DSM - PIT
    5h 25m
    $114–573

  8. Fly to Lehigh Valley International Airport

    1. Fly from Des Moines (DSM) to Lehigh Valley International Airport (ABE)plane plane DSM - ABE
    5h 32m
    $106–523

  9. Fly to Laguardia Airport, train

    1. Fly from Des Moines (DSM) to Laguardia Airport (LGA)plane plane DSM - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    5h 15m
    $174–1,283

  10. Bus via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago Bus Station to Philadelphia Bus Stationbus bus FlixBus N2642
    28h 15m
    $201–310

  11. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to 30th Street Stationtrain train Cardinal
    34h 15m
    $613–994

Des Moines to Pennsylvania by bus (Greyhound)

Calendar7Weekly Buses
Duration27hAverage Duration
Ticket$203Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Pennsylvania.ExpandLaunch map view
  • Distance: 984.3 mi
  • Duration: 3h 41m

What companies run services between Des Moines, IA, USA and Pennsylvania, USA?

American Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Philadelphia International Airport (PHL) every 2 hours. Alternatively, you can take a bus from Des Moines to Philadelphia Bus Station via Indianapolis Union Station in around 27h.

Airlines
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Want to know more about travelling around United States

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Need to know: Greyhound

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