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How to get fromDes Moines to Pittsburghby plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Greyhound)

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There are 9 ways to get from Des Moines to Pittsburgh by plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Pittsburgh International Airport

    best
    1. Fly from Des Moines (DSM) to Pittsburgh International Airport (PIT)plane plane DSM - PIT
    5h 16m
    $128–621

  2. Drive to Fort Dodge Municipal Airport, fly to Pittsburgh International Airport

    cheapest
    1. Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Pittsburgh International Airport (PIT)plane plane FOD - PIT
    7h 50m
    $107–505

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    17h 39m
    $167–379

  4. Bus via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago to Pittsburgh Intermodal Stationbus bus FlixBus N2640
    19h 26m
    $122–217

  5. Drive  776 mi

    1. Drive from Des Moines to Pittsburghcar car 776 mi
    12h 49m
    $142–205

  6. Fly Des Moines to Morgantown Municipal Airport, bus

    1. Fly from Des Moines (DSM) to Morgantown Municipal Airport (MGW)plane plane DSM - MGW
    2. Take the bus from Morgantown Mountaineer Station WVU to Pittsburgh Intermodal Stationbus bus
    8h 29m
    $133–554

  7. Fly Des Moines to Johnstown-Cambria County Airport, train

    1. Fly from Des Moines (DSM) to Johnstown-Cambria County Airport (JST)plane plane DSM - JST
    2. Take the train from Johnstown Amtrak Station to Pittsburgh Amtrak Stationtrain train
    7h 30m
    $152–634

  8. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    18h 50m
    $189–445

  9. Bus (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Pittsburgh Intermodal Stationbus bus Greyhound US0421
    19h 30m
    $115–223

Des Moines to Pittsburgh by bus, foot, and train

Calendar7Weekly Services
Duration17h 39mAverage Duration
Ticket$167Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Pittsburgh.ExpandLaunch map view
  • Distance: 733.5 mi
  • Duration: 5h 16m

What companies run services between Des Moines, IA, USA and Pittsburgh, PA, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Pittsburgh International Airport (PIT) hourly. Alternatively, you can take a bus from Des Moines to Pittsburgh Intermodal Station via Chicago Bus Station, Jackson & Clinton, Jackson & Dearborn, Jackson-Red, 95th, and Chicago in around 19h 26m.

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