There are 7 ways to get from Des Moines to Plymouth by plane, bus, train, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Boston Logan Airport, bus
best- Fly from Des Moines (DSM) to Boston Logan Airport (BOS)plane DSM - BOS
- Take the bus from Logan International Airport to Park & Ride Lot, Ex 13 Info. Ctr.bus
5h 2m$167–697Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Bostontrain
- Take the bus from Boston South Buses to Park & Ride Lot, Ex 13 Info. Ctr.bus
31h 53m$378–818Bus
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to New York Midtownbus
- Take the bus from New York Midtown to Bostonbus
- Take the bus from Boston South Buses to Park & Ride Lot, Ex 13 Info. Ctr.bus
32h 2m$228–403Drive 1,315.5 mi
- Drive from Des Moines to Plymouthcar 1,315.5 mi
22h 30m$241–347Fly to Barnstable Municipal Airport
- Fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA)plane DSM - HYA
7h 14m$202–846Fly to Manchester Airport, bus
- Fly from Des Moines (DSM) to Manchester Airport (MHT)plane DSM - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
- Take the bus from Boston South Buses to Park & Ride Lot, Ex 13 Info. Ctr.bus
8h 54m$183–760Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Bostontrain
- Take the bus from Boston South Buses to Park & Ride Lot, Ex 13 Info. Ctr.bus
33h 4m$409–892
Des Moines to Plymouth by bus, foot, and train
Questions & Answers
The cheapest way to get from Des Moines to Plymouth is to bus which costs $220 - $410 and takes 32h 2m.
The fastest way to get from Des Moines to Plymouth is to fly and bus which takes 5h 2m and costs $160 - $700.
No, there is no direct bus from Des Moines to Plymouth. However, there are services departing from Des Moines and arriving at Park & Ride Lot, Ex 13 Info. Ctr. via Chicago Bus Station, New York Midtown and Boston South Buses. The journey, including transfers, takes approximately 32h 2m.
The distance between Des Moines and Plymouth is 1220 miles. The road distance is 1323.2 miles.
The best way to get from Des Moines to Plymouth without a car is to bus and train which takes 31h 53m and costs $370 - $850.
It takes approximately 5h 2m to get from Des Moines to Plymouth, including transfers.
Des Moines to Plymouth bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Plymouth is to bus which takes 32h 2m and costs $220 - $410. Alternatively, you can fly, which costs $200 - $850 and takes 7h 14m.
Des Moines to Plymouth bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Plymouth is 1h ahead of Des Moines. It is currently 5:44 PM in Des Moines and 6:44 PM in Plymouth.
What companies run services between Des Moines, IA, USA and Plymouth, MA, USA?
You can take a bus from Des Moines to Park & Ride Lot, Ex 13 Info. Ctr. via Chicago Bus Station, New York Midtown, Boston, and Boston South Buses in around 32h 2m. Alternatively, American Airlines, Allegiant Air, and Cape Air fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA) once daily.
- Website
- aa.com
Flights from Des Moines to Boston Logan Airport via Philadelphia
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Boston Logan Airport via Chicago O'Hare
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Barnstable Municipal Airport via New York La Guardia
- Ave. Duration
- 5h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–800
Flights from Des Moines to Barnstable Municipal Airport via Reagan Washington
- Ave. Duration
- 9h 32m
- When
- Saturday and Sunday
- Estimated price
- $180–850
Flights from Des Moines to Manchester Airport via Reagan Washington
- Ave. Duration
- 7h 30m
- When
- Saturday and Sunday
- Estimated price
- $160–750
Flights from Des Moines to Manchester Airport via Chicago O'Hare
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Manchester Airport via Charlotte
- Ave. Duration
- 7h 26m
- When
- Sunday
- Estimated price
- $180–850
Flights from Des Moines to Manchester Airport via Philadelphia
- Ave. Duration
- 7h 46m
- When
- Every day
- Estimated price
- $160–750
- Website
- southwest.com
Flights from Des Moines to Boston Logan Airport via Chicago Midway
- Ave. Duration
- 5h 6m
- When
- Saturday to Wednesday
- Estimated price
- $130–650
Flights from Des Moines to Manchester Airport via Chicago Midway
- Ave. Duration
- 4h 56m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $140–700
- Website
- delta.com
Flights from Des Moines to Boston Logan Airport via Detroit
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 5h 7m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–650
- Website
- united.com
Flights from Des Moines to Boston Logan Airport via Chicago O'Hare
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $130–650
- Website
- allegiantair.com
Flights from Des Moines to Boston Logan Airport
- Ave. Duration
- 2h 48m
- When
- Monday and Friday
- Estimated price
- $130–650
- Website
- capeair.com
Flights from Des Moines to Barnstable Municipal Airport via Boston Logan Airport
- Ave. Duration
- 4h 35m
- When
- Monday
- Estimated price
- $170–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Boston
- Ave. Duration
- 22h 2m
- Frequency
- Once daily
- Estimated price
- $310–700
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $50–110
- Website
- Amtrak
Train from Chicago Union Station to Boston
- Ave. Duration
- 22h 2m
- Frequency
- Once daily
- Estimated price
- $310–700
- Website
- Amtrak
- Phone
- +1 (508) 746-0378
- [email protected]
- Website
- Plymouth & Brockton
Bus from Logan International Airport to Park & Ride Lot, Ex 13 Info. Ctr.
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $19–26
- Website
- Plymouth & Brockton
- One Way - Adult
- $19–26
Bus from Boston South Buses to Park & Ride Lot, Ex 13 Info. Ctr.
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $18–24
- Website
- Plymouth & Brockton
- One Way - Adult
- $18–24
Bus from Boston South Buses to Park & Ride Lot, Ex 13 Info. Ctr.
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $18–24
- Website
- Plymouth & Brockton
- One Way - Adult
- $18–24
Bus from Boston South Buses to Park & Ride Lot, Ex 13 Info. Ctr.
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $18–24
- Website
- Plymouth & Brockton
- One Way - Adult
- $18–24
Bus from Boston South Buses to Park & Ride Lot, Ex 13 Info. Ctr.
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $18–24
- Website
- Plymouth & Brockton
- One Way - Adult
- $18–24
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–95
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–95
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to New York Midtown
- Ave. Duration
- 17h 5m
- Frequency
- Twice daily
- Estimated price
- $130–230
- Schedules at
- Flixbus USA
Bus from New York Midtown to Boston
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Des Moines to Plymouth is 1323 miles. It takes approximately 22h 30m to drive from Des Moines to Plymouth.
There are 135+ hotels available in Plymouth.







