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How to get fromDes Moines to Port Charlotteby plane, taxi, bus (Greyhound, Flixbus, Amtrak), bus, train, or car

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There are 6 ways to get from Des Moines to Port Charlotte by plane, taxi, bus (Greyhound, Flixbus, Amtrak), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ft. Myers, taxi

    best
    1. Fly from Des Moines (DSM) to Ft. Myers (RSW)plane plane DSM - RSW
    2. Take the taxi from Ft-Myers-Airport-RSW to Port Charlottetaxi taxi
    4h 1m
    $269–823

  2. Fly to Punta Gorda Airport

    cheapest
    1. Fly from Des Moines (DSM) to Punta Gorda Airport (PGD)plane plane DSM - PGD
    3h 23m
    $135–533

  3. Bus, Amtrak Thruway

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Union Station to Port Charlottebus bus
    36h 36m

  4. Bus, train, Amtrak Thruway

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Tampatrain train
    3. Take the bus from Tampa Union Station to Port Charlottebus bus
    2d 5h

  5. Drive  1,410 mi

    1. Drive from Des Moines to Port Charlottecar car 1,410 mi
    25h 4m
    $241–349

  6. Fly to Sarasota–Bradenton International Airport, Amtrak Thruway

    1. Fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ)plane plane DSM - SRQ
    2. Take the bus from Sarasota Amtrak Bus Stop to Port Charlottebus bus
    6h 12m

Des Moines (DSM) to Ft. Myers (RSW) flights

Calendar77Weekly Planes
Duration5h 9mAverage Duration
Ticket$129Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Port Charlotte.ExpandLaunch map view
  • Distance: 1,287.6 mi
  • Duration: 4h 1m

What companies run services between Des Moines, IA, USA and Port Charlotte, FL, USA?

You can take a bus from Des Moines to Port Charlotte via Indianapolis Union Station, Atlanta Bus Station, Marion Transit Center, Nebraska Av @ Twiggs St, Tampa Union Station, and Port Charlotte in around 36h 36m. Alternatively, Allegiant Air flies from Des Moines (DSM) to Punta Gorda Airport (PGD) 3 times a week.

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