Rome2Rio

How to get fromDes Moines to Port Charlotteby plane, taxi, bus (Greyhound, Flixbus, Amtrak), bus, train, or car

Find Transport to Port Charlotte

See all options

There are 6 ways to get from Des Moines to Port Charlotte by plane, taxi, bus (Greyhound, Flixbus, Amtrak), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ft. Myers, taxi

    best
    1. Fly from Des Moines (DSM) to Ft. Myers (RSW)plane plane DSM - RSW
    2. Take the taxi from Ft-Myers-Airport-RSW to Port Charlottetaxi taxi
    4h 1m
    $328–1,031

  2. Fly to Punta Gorda Airport

    cheapest
    1. Fly from Des Moines (DSM) to Punta Gorda Airport (PGD)plane plane DSM - PGD
    3h 23m
    $204–841

  3. Bus, Amtrak Thruway

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Union Station to Port Charlottebus bus
    33h 31m
    $275–495

  4. Bus, train, Amtrak Thruway

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Tampatrain train
    3. Take the bus from Tampa Union Station to Port Charlottebus bus
    2d 4h

  5. Drive 1,410 mi

    1. Drive from Des Moines to Port Charlottecar car 1,410 mi
    25h 5m
    $258–372

  6. Fly to Sarasota–Bradenton International Airport, Amtrak Thruway

    1. Fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ)plane plane DSM - SRQ
    2. Take the bus from Sarasota Amtrak Bus Stop to Port Charlottebus bus
    6h 33m
    $274–1,157

Des Moines (DSM) to Ft. Myers (RSW) flights

Calendar51Weekly Planes
Duration5h 35mAverage Duration
Ticket$188Cheapest Price
See schedules

Questions & Answers

Map of how to get from Des Moines to Port Charlotte.ExpandLaunch map view
  • Distance: 1,287.6 mi
  • Duration: 4h 1m

What companies run services between Des Moines, IA, USA and Port Charlotte, FL, USA?

You can take a bus from Des Moines to Port Charlotte via St Louis Bus Station, Atlanta Bus Station, Tampa Bus Station, Marion Transit Center, Nebraska Av @ Twiggs St, Tampa Union Station, and Port Charlotte in around 33h 31m. Alternatively, Allegiant Air flies from Des Moines (DSM) to Punta Gorda Airport (PGD) 3 times a week.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers