There are 3 ways to get from Des Moines to Prairie du Chien by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, drive
best- Take the bus from Des Moines to Owatonnabus
- Take the bus from Owatonna to Rochesterbus
- Take the bus from Rochester to La Crossebus
- Drive from La Crosse to Prairie du Chiencar
10h 1m$95–167Drive 198.8 mi
cheapest- Drive from Des Moines to Prairie du Chiencar 198.8 mi
4h 7m$37–53Fly, drive
- Fly from Des Moines (DSM) to La Crosse (LSE)plane DSM - LSE
- Drive from La-Crosse-Airport-LSE to Prairie du Chiencar
6h 5m$110–521
Des Moines (DSM) to La Crosse (LSE) flights
Comparing Your Travel Options
The cheapest way to get from Des Moines to Prairie du Chien is to drive which costs $35 - $55 and takes 4h 7m.
The fastest way to get from Des Moines to Prairie du Chien is to drive which takes 4h 7m and costs $35 - $55.
The distance between Des Moines and Prairie du Chien is 368 miles. The road distance is 199.9 miles.
It takes approximately 10h 1m to get from Des Moines to Prairie du Chien, including transfers.
Yes, the driving distance between Des Moines to Prairie du Chien is 200 miles. It takes approximately 4h 7m to drive from Des Moines to Prairie du Chien.
There are 20+ hotels available in Prairie du Chien.
What companies run services between Des Moines, IA, USA and Prairie du Chien, WI, USA?
There is no direct connection from Des Moines to Prairie du Chien. However, you can take the bus to Owatonna, take the bus to Rochester, take the bus to La Crosse, then drive to Prairie du Chien. Alternatively, you can drive from Des Moines to Prairie du Chien in around 4h 7m.
- Website
- aa.com
Flights from Des Moines to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $80–480
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Owatonna
- Ave. Duration
- 4h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Rochester to La Crosse
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
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