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How to get fromDes Moines to Puebloby plane, bus, bus (Greyhound), car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Des Moines to Pueblo by plane, bus, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Colorado Springs Airport, bus

    best
    1. Fly from Des Moines (DSM) to Colorado Springs Airport (COS)plane plane DSM - COS
    2. Take the bus from Colorado Springs, CO to Pueblo, CObus bus
    6h 57m
    $157–665
  2. Fly to San Luis Valley Regional Airport, drive

    cheapest
    1. Fly from Des Moines (DSM) to San Luis Valley Regional Airport (ALS)plane plane DSM - ALS
    2. Drive from San Luis Valley Regional Airport (ALS) to Pueblocar car
    7h 27m
    $125–496
  3. Bus via Omaha

    1. Take the bus from Des Moines to Omaha, NEbus bus
    2. Take the bus from Omaha, NE to Denverbus bus
    3. Take the bus from Denver to Pueblo, CObus bus
    16h 57m
    $210–288
  4. Drive 734 mi

    1. Drive from Des Moines to Pueblocar car 734 mi
    12h 34m
    $134–194
  5. Fly to Denver, bus

    1. Fly from Des Moines (DSM) to Denver (DEN)plane plane DSM - DEN
    2. Take the bus from Denver Union Station to Pueblo Transitbus bus
    5h 57m
    $156–666
  6. Fly to Pueblo Memorial Airport

    1. Fly from Des Moines (DSM) to Pueblo Memorial Airport (PUB)plane plane DSM - PUB
    5h 32m
    $173–626
  7. Bus

    1. Take the bus from Des Moines to Denver Union Stationbus bus Greyhound US0123S
    2. Take the bus from Denver Union Station to Pueblo Transitbus bus Greyhound US1144 / ...
    17h 35m
    $128–240

Des Moines to Pueblo by bus and foot

Calendar7Weekly Services
Duration16h 57mAverage Duration
Ticket$210Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Pueblo, CO, USA?

You can take a bus from Des Moines to Pueblo, CO via Omaha, NE, Denver, 11th St & Auraria Pkwy, Stout St & 21st St, and Denver in around 16h 57m. Alternatively, United Airlines, Key Lime, and three other airlines fly from Des Moines (DSM) to Pueblo Memorial Airport (PUB) 5 times a day.

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