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How to get fromDes Moines to Puebloby plane, bus, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Find Transport to Pueblo

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There are 8 ways to get from Des Moines to Pueblo by plane, bus, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Denver, bus

    best
    1. Fly from Des Moines (DSM) to Denver (DEN)plane plane DSM - DEN
    2. Take the bus from Denver Union Station to Pueblo Transitbus bus
    6h 2m
    $136–652

  2. Drive to Fort Dodge Municipal Airport, fly to Denver, bus

    cheapest
    1. Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Denver (DEN)plane plane FOD - DEN
    3. Take the bus from Denver Union Station to Pueblo Transitbus bus
    7h 46m
    $104–464

  3. Bus via Omaha

    1. Take the bus from Des Moines to Omaha, NEbus bus
    2. Take the bus from Omaha to Denverbus bus
    3. Take the bus from Denver to Pueblobus bus
    17h 30m
    $192–259

  4. Drive  734 mi

    1. Drive from Des Moines to Pueblocar car 734 mi
    12h 34m
    $134–194

  5. Fly Des Moines to Colorado Springs Airport, bus

    1. Fly from Des Moines (DSM) to Colorado Springs Airport (COS)plane plane DSM - COS
    2. Take the bus from Colorado Springs to Pueblo, CObus bus
    7h 1m
    $163–682

  6. Fly Des Moines to Pueblo Memorial Airport

    1. Fly from Des Moines (DSM) to Pueblo Memorial Airport (PUB)plane plane DSM - PUB
    5h 32m
    $164–678

  7. Fly Des Moines to San Luis Valley Regional Airport, drive

    1. Fly from Des Moines (DSM) to San Luis Valley Regional Airport (ALS)plane plane DSM - ALS
    2. Drive from San Luis Valley Regional Airport (ALS) to Pueblocar car
    7h 36m
    $126–508

  8. Bus

    1. Take the bus from Des Moines to Denver Union Stationbus bus Greyhound US0123S
    2. Take the bus from Denver Union Station to Pueblo Transitbus bus Greyhound US1144 / ...
    17h 35m
    $128–201

Des Moines to Pueblo by bus

Calendar7Weekly Buses
Duration17h 30mAverage Duration
Ticket$192Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Pueblo.ExpandLaunch map view
  • Distance: 731.8 mi
  • Duration: 6h 2m

What companies run services between Des Moines, IA, USA and Pueblo, CO, USA?

You can take a bus from Des Moines to Pueblo via Omaha and Denver in around 17h 30m. Alternatively, United Airlines, Key Lime, and two other airlines fly from Des Moines (DSM) to Pueblo Memorial Airport (PUB) every 4 hours.

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