There are 8 ways to get from Des Moines to Pueblo by plane, bus, bus (Greyhound), car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Des Moines to Colorado Springs Airport, bus
best- Fly from Des Moines (DSM) to Colorado Springs Airport (COS)plane DSM - COS
- Take the bus from Colorado Springs, CO to Pueblo, CObus
6h 57m$132–545Fly Des Moines to San Luis Valley Regional Airport, drive
cheapest- Fly from Des Moines (DSM) to San Luis Valley Regional Airport (ALS)plane DSM - ALS
- Drive from San Luis Valley Regional Airport (ALS) to Pueblocar
6h 55m$110–436Bus via Omaha
- Take the bus from Des Moines to Omaha, NEbus
- Take the bus from Omaha, NE to Denverbus
- Take the bus from Denver to Pueblo, CObus
16h 57m$207–284Drive 734 mi
- Drive from Des Moines to Pueblocar 734 mi
12h 34m$134–194Fly Des Moines to Denver, bus
- Fly from Des Moines (DSM) to Denver (DEN)plane DSM - DEN
- Take the bus from Denver Union Station to Pueblo Transitbus
5h 57m$128–551Fly Des Moines to Pueblo Memorial Airport
- Fly from Des Moines (DSM) to Pueblo Memorial Airport (PUB)plane DSM - PUB
5h 32m$153–566Drive to Fort Dodge Municipal Airport, fly to Denver, bus
- Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car
- Fly from Fort Dodge Municipal Airport (FOD) to Denver (DEN)plane FOD - DEN
- Take the bus from Denver Union Station to Pueblo Transitbus
7h 53m$112–465Bus
- Take the bus from Des Moines to Denver Union Stationbus Greyhound US0123S
- Take the bus from Denver Union Station to Pueblo Transitbus Greyhound US1144 / ...
17h 35m$112–212
Des Moines to Pueblo by bus and foot
Questions & Answers
The cheapest way to get from Des Moines to Pueblo is to bus which costs $110 - $220 and takes 17h 35m.
The fastest way to get from Des Moines to Pueblo is to fly which takes 5h 32m and costs $150 - $600.
No, there is no direct bus from Des Moines to Pueblo. However, there are services departing from Des Moines and arriving at Pueblo, CO via Omaha, NE, 11th St & Auraria Pkwy and Denver. The journey, including transfers, takes approximately 16h 57m.
The distance between Des Moines and Pueblo is 679 miles. The road distance is 738.3 miles.
The best way to get from Des Moines to Pueblo without a car is to bus via Omaha which takes 16h 57m and costs $200 - $290.
It takes approximately 6h 57m to get from Des Moines to Pueblo, including transfers.
Des Moines to Pueblo bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Pueblo is to bus via Omaha which takes 16h 57m and costs $200 - $290. Alternatively, you can fly, which costs $150 - $600 and takes 5h 32m.
Des Moines to Pueblo bus services, operated by Greyhound USA, arrive at Omaha, NE station.
Pueblo is 1h behind Des Moines. It is currently 2:16 AM in Des Moines and 1:16 AM in Pueblo.
What companies run services between Des Moines, IA, USA and Pueblo, CO, USA?
You can take a bus from Des Moines to Pueblo, CO via Omaha, NE, Denver, 11th St & Auraria Pkwy, Stout St & 21st St, and Denver in around 16h 57m. Alternatively, United Airlines, Key Lime, and three other airlines fly from Des Moines (DSM) to Pueblo Memorial Airport (PUB) 5 times a day.
- Website
- united.com
Flights from Des Moines to Colorado Springs Airport via Denver
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $85–480
Flights from Des Moines to Colorado Springs Airport via Chicago O'Hare
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Denver
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $85–490
Flights from Fort Dodge Municipal Airport to Denver
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $70–400
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from Colorado Springs, CO to Pueblo, CO
- Ave. Duration
- 55 min
- Frequency
- Twice daily
- Estimated price
- $25–40
- Website
- Limousine Express
- One Way
- $25–40
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More Questions & Answers
Yes, the driving distance between Des Moines to Pueblo is 738 miles. It takes approximately 12h 34m to drive from Des Moines to Pueblo.
Book your Des Moines to Pueblo bus tickets online with Omio.
There are 61+ hotels available in Pueblo.




