There are 5 ways to get from Des Moines to Quad Cities by plane, bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Range Regional Airport
best- Fly from Des Moines (DSM) to Range Regional Airport (HIB)plane DSM - HIB
4h 1m$134–438Drive 436.2 mi
cheapest- Drive from Des Moines to Quad Citiescar 436.2 mi
7h 15m$80–115Bus
- Take the bus from Des Moines to St. Paulbus
- Take the bus from St. Paul to Duluthbus
- Take the bus from Duluth to Virginiabus
10h 23m$138–199Fly to International Falls, drive
- Fly from Des Moines (DSM) to International Falls (INL)plane DSM - INL
- Drive from International Falls (INL) to Quad Citiescar
5h 27m$96–409Bus via Minneapolis
- Take the bus from Des Moines to Minneapolis Bus Stationbus
- Take the bus from Minneapolis to Duluthbus
- Take the bus from Duluth to Virginiabus
10h 53m$122–180
Des Moines (DSM) to Range Regional Airport (HIB) flights
Comparing Your Travel Options
The cheapest way to get from Des Moines to Quad Cities is to drive which costs $75 - $120 and takes 7h 15m.
The fastest way to get from Des Moines to Quad Cities is to fly which takes 4h 1m and costs $130 - $440.
No, there is no direct bus from Des Moines to Quad Cities. However, there are services departing from Des Moines and arriving at Virginia via St. Paul and Duluth. The journey, including transfers, takes approximately 10h 23m.
The distance between Des Moines and Quad Cities is 439 miles. The road distance is 438.7 miles.
The best way to get from Des Moines to Quad Cities without a car is to bus which takes 10h 23m and costs $130 - $200.
It takes approximately 4h 1m to get from Des Moines to Quad Cities, including transfers.
Des Moines to Quad Cities bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Des Moines to Quad Cities is to fly which takes 4h 1m and costs $130 - $440. Alternatively, you can bus, which costs $130 - $200 and takes 10h 23m.
Des Moines to Quad Cities bus services, operated by Jefferson Lines, arrive at St. Paul station.
Yes, the driving distance between Des Moines to Quad Cities is 439 miles. It takes approximately 7h 15m to drive from Des Moines to Quad Cities.
What companies run services between Des Moines, IA, USA and Quad Cities, MN, USA?
Delta flies from Des Moines (DSM) to Range Regional Airport (HIB) twice daily. Alternatively, you can take a bus from Des Moines to Quad Cities via St. Paul, Duluth, and Virginia in around 10h 23m.
- Website
- delta.com
Flights from Des Moines to Range Regional Airport via Minneapolis
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $55–340
Flights from Des Moines to International Falls via Minneapolis
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $60–360
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 40m
- Frequency
- Twice daily
- Estimated price
- $60–90
- Book at
- Jefferson Lines
- Adult
- $60–90
Bus from St. Paul to Duluth
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $40–60
- Book at
- Jefferson Lines
- Adult
- $40–60
Bus from Duluth to Virginia
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a week
- Estimated price
- $26–40
- Book at
- Jefferson Lines
- Adult
- $26–40
Bus from Minneapolis to Duluth
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $45–65
- Book at
- Jefferson Lines
- Adult
- $45–65
Bus from Duluth to Virginia
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a week
- Estimated price
- $26–40
- Book at
- Jefferson Lines
- Adult
- $26–40
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Minneapolis Bus Station
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are six+ hotels available in Quad Cities.