There are 3 ways to get from Des Moines to Saint Charles by plane, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Des Moines to Saint Charles by bus and train (Greyhound)
Questions & Answers
The cheapest way to get from Des Moines to Saint Charles is to drive which costs $55 - $85 and takes 6h 19m.
The fastest way to get from Des Moines to Saint Charles is to fly which takes 5h 8m and costs $160 - $850.
No, there is no direct bus from Des Moines to Saint Charles. However, there are services departing from Des Moines and arriving at 4375 Rider Trail North Sb via North Hanley Transit Center. The journey, including transfers, takes approximately 9h 45m.
The distance between Des Moines and Saint Charles is 282 miles. The road distance is 311.9 miles.
The best way to get from Des Moines to Saint Charles without a car is to bus which takes 9h 45m and costs $70 - $130.
It takes approximately 5h 8m to get from Des Moines to Saint Charles, including transfers.
Des Moines to Saint Charles bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Saint Charles is to fly which takes 5h 8m and costs $160 - $850. Alternatively, you can bus, which costs $70 - $130 and takes 9h 45m.
Des Moines to Saint Charles bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Des Moines to Saint Charles is 312 miles. It takes approximately 6h 19m to drive from Des Moines to Saint Charles.
What companies run services between Des Moines, IA, USA and Saint Charles, MO, USA?
Delta, United Airlines, and two other airlines fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Greyhound USA operates a bus from Des Moines to St Louis Bus Station once daily. Tickets cost $65–130 and the journey takes 8h 20m.
- Website
- aa.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $240–1,100
- Website
- united.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $270–1,200
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $150–800
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 56m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $270–1,200
- Website
- delta.com
Flights from Des Moines to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $160–850
Flights from Des Moines to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $250–1,200
Flights from Des Moines to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $210–1,000
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
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More Questions & Answers
There are 208+ hotels available in Saint Charles.