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How to get fromDes Moines to Saint Charlesby bus, shuttle, car, plane, taxi, or train

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There are 6 ways to get from Des Moines to Saint Charles by bus, shuttle, car, plane, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, shuttle

    best
    1. Take the bus from Des Moines to Owatonnabus bus Jefferson Lines 804 / ...
    2. Take a shuttle bus from Owatonna, MN to Rochester Sinclairshuttle bus S MN Conn
    6h 34m
    $133–206

  2. Drive 221.6 mi

    cheapest
    1. Drive from Des Moines to Saint Charlescar car 221.6 mi
    3h 39m
    $41–59

  3. Fly to Rochester, taxi

    1. Fly from Des Moines (DSM) to Rochester (RST)plane plane DSM - RST
    2. Take the taxi from Rochester-Airport-RST to Saint Charlestaxi taxi
    4h 39m
    $178–611

  4. Bus

    1. Take the bus from Des Moines to St. Paulbus bus Jefferson Lines 806 / ...
    2. Take the bus from St. Paul to Rochesterbus bus Jefferson Lines 965
    7h 33m
    $168–224

  5. Bus, train

    1. Take the bus from Des Moines to St. Paulbus bus Jefferson Lines 806 / ...
    2. Take the train from St. Paul-Minneapolis to Winonatrain train Empire Builder / ...
    8h 17m
    $185–269

  6. Fly to La Crosse, taxi

    1. Fly from Des Moines (DSM) to La Crosse (LSE)plane plane DSM - LSE
    2. Take the taxi from La-Crosse-Airport-LSE to Saint Charlestaxi taxi
    5h 18m
    $283–781

Des Moines (DSM) to Rochester (RST) flights

Calendar62Weekly Planes
Duration5h 38mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Saint Charles.ExpandLaunch map view
  • Distance: 253.8 mi
  • Duration: 6h 34m

What companies run services between Des Moines, IA, USA and Saint Charles, MN, USA?

You can take a bus from Des Moines to Saint Charles via St. Paul and Rochester in around 7h 33m.

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