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How to get fromDes Moines to Salisburyby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Des Moines to Salisbury by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Salisbury–Ocean City–Wicomico Regional Airport

    best
    1. Fly from Des Moines (DSM) to Salisbury–Ocean City–Wicomico Regional Airport (SBY)plane plane DSM - SBY
    6h 25m
    $218–896

  2. Drive 1,109.2 mi

    cheapest
    1. Drive from Des Moines to Salisburycar car 1,109.2 mi
    19h 12m
    $203–293

  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore, MD - Greyhound Bus Terminal Downtown to Salisbury, MDbus bus
    29h 20m
    $245–424

  4. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Rockville Amtraktrain train
    4. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    5. Take the bus from BWI Amtrak Station to Salisbury, MDbus bus
    30h 20m
    $360–1,271

  5. Fly to Baltimore-Washington International Airport, bus

    1. Fly from Des Moines (DSM) to Baltimore-Washington International Airport (BWI)plane plane DSM - BWI
    2. Take the bus from BWI-Thurgood Marshall Airport to Salisbury, MDbus bus
    7h 27m
    $263–931

  6. Fly to Ronald Reagan Washington National Airport, train, bus

    1. Fly from Des Moines (DSM) to Ronald Reagan Washington National Airport (DCA)plane plane DSM - DCA
    2. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    3. Take the bus from BWI Amtrak Station to Salisbury, MDbus bus
    6h 41m
    $259–1,628

  7. Bus via Harrisburg

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus bus
    3. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus
    4. Take the bus from Baltimore, MD - Greyhound Bus Terminal Downtown to Salisbury, MDbus bus
    30h 15m
    $266–436

  8. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Baltimore Penn Stationtrain train
    3. Take the bus from BWI Amtrak Station to Salisbury, MDbus bus
    36h 23m
    $387–1,344

Des Moines to Salisbury by bus

Calendar28Weekly Buses
Duration29h 20mAverage Duration
Ticket$245Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Salisbury.ExpandLaunch map view
  • Distance: 996 mi
  • Duration: 6h 25m

What companies run services between Des Moines, IA, USA and Salisbury, MD, USA?

American Airlines and Allegiant Air fly from Des Moines (DSM) to Salisbury–Ocean City–Wicomico Regional Airport (SBY) 3 times a day. Alternatively, you can take a bus from Des Moines to Salisbury, MD via Chicago Bus Station, Baltimore Downtown Bus Station, and Baltimore, MD - Greyhound Bus Terminal Downtown in around 29h 20m.

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