There are 6 ways to get from Des Moines to San Antonio by plane, bus (Flixbus), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to San Antonio International Airport
best- Fly from Des Moines (DSM) to San Antonio International Airport (SAT)plane DSM - SAT
5h 22m$200–923Drive 953.1 mi
cheapest- Drive from Des Moines to San Antoniocar 953.1 mi
15h 57m$174–252Bus via Denton
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to Dentonbus
- Take the bus from Denton to San Antonio Bus Stationbus
22h 35m$188–312Bus, train
- Take the bus from Des Moines to St Louis Bus Stationbus Greyhound US0153S
- Take the train from St. Louis to San Antonio Stationtrain Texas Eagle
35h 56m$394–820Fly to Austin-Bergstrom International Airport, bus
- Fly from Des Moines (DSM) to Austin-Bergstrom International Airport (AUS)plane DSM - AUS
- Take the bus from Austin Eastside Bus Plaza to San Antonio Bus Stationbus
5h 39m$202–898Bus
- Take the bus from Des Moines to Omaha, NEbus Greyhound US0123S
- Take the bus from Omaha to San Antoniobus Omaha-Aguascalientes
25h 40m$262–281
Des Moines to San Antonio by bus
Questions & Answers
The cheapest way to get from Des Moines to San Antonio is to drive which costs $170 - $260 and takes 15h 57m.
The fastest way to get from Des Moines to San Antonio is to fly which takes 5h 22m and costs $200 - $950.
No, there is no direct bus from Des Moines to San Antonio station. However, there are services departing from Des Moines and arriving at San Antonio Bus Station via Kansas City Bus Station and Denton. The journey, including transfers, takes approximately 22h 35m.
The distance between Des Moines and San Antonio is 893 miles. The road distance is 958.7 miles.
The best way to get from Des Moines to San Antonio without a car is to bus via Denton which takes 22h 35m and costs $180 - $320.
It takes approximately 5h 22m to get from Des Moines to San Antonio, including transfers.
Des Moines to San Antonio bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Des Moines to San Antonio is to fly which takes 5h 22m and costs $200 - $950. Alternatively, you can bus via Denton, which costs $180 - $320 and takes 22h 35m.
Des Moines to San Antonio bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Des Moines to San Antonio is 959 miles. It takes approximately 15h 57m to drive from Des Moines to San Antonio.
What companies run services between Des Moines, IA, USA and San Antonio, TX, USA?
American Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to San Antonio International Airport (SAT) hourly. Alternatively, you can take a bus from Des Moines to San Antonio Bus Station via Kansas City, Kansas City Bus Station, and Denton in around 22h 35m.
- Website
- aa.com
Flights from Des Moines to San Antonio International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $180–900
Flights from Des Moines to San Antonio International Airport via Chicago O'Hare
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Des Moines to Austin-Bergstrom International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $170–850
- Website
- united.com
Flights from Des Moines to San Antonio International Airport via Houston
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $190–950
Flights from Des Moines to San Antonio International Airport via Denver
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Des Moines to San Antonio International Airport via Chicago O'Hare
- Ave. Duration
- 7h 18m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Des Moines to Austin-Bergstrom International Airport via Houston
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $190–950
- Website
- southwest.com
Flights from Des Moines to San Antonio International Airport via Chicago Midway
- Ave. Duration
- 7h 21m
- When
- Tuesday to Friday
- Estimated price
- $240–1,100
Flights from Des Moines to San Antonio International Airport via Denver
- Ave. Duration
- 8h 5m
- When
- Monday to Saturday
- Estimated price
- $250–1,100
Flights from Des Moines to Austin-Bergstrom International Airport via Chicago Midway
- Ave. Duration
- 4h 50m
- When
- Saturday and Sunday
- Estimated price
- $240–1,100
Flights from Des Moines to Austin-Bergstrom International Airport via Denver
- Ave. Duration
- 4h 55m
- When
- Tuesday and Wednesday
- Estimated price
- $250–1,100
- Website
- delta.com
Flights from Des Moines to San Antonio International Airport via Minneapolis
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $240–1,100
- Website
- allegiantair.com
Flights from Des Moines to Austin-Bergstrom International Airport
- Ave. Duration
- 2h 5m
- When
- Thursday and Sunday
- Estimated price
- $170–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to San Antonio Station
- Ave. Duration
- 26h 36m
- Frequency
- Once daily
- Estimated price
- $330–700
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Kansas City Bus Station to Denton
- Ave. Duration
- 9h 35m
- Frequency
- 6 times a week
- Estimated price
- $85–150
- Schedules at
- flixbus.com
Bus from Denton to San Antonio Bus Station
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $50–90
- Schedules at
- flixbus.com
Bus from Austin Eastside Bus Plaza to San Antonio Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $13–22
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from Austin Eastside Bus Plaza to San Antonio Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Des Moines to Omaha, NE
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +52 449 291 3048
- [email protected]
- Website
- facebook.com
Bus from Omaha to San Antonio
- Ave. Duration
- 21h
- Frequency
- Twice a week
- Estimated price
- $238
- Schedules at
- facebook.com
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