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How to get fromDes Moines to Sedaliaby bus, train, car, or plane

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There are 5 ways to get from Des Moines to Sedalia by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson 803 / ...
    2. Take the train from Kansas City to Sedalia Amtrak Stationtrain train Lincoln Service Missouri River Runner / ...
    6h 57m
    $83–138

  2. Drive 226.4 mi

    cheapest
    1. Drive from Des Moines to Sedaliacar car 226.4 mi
    5h 6m
    $42–60

  3. Fly to Columbia Regional Airport, drive

    1. Fly from Des Moines (DSM) to Columbia Regional Airport (COU)plane plane DSM - COU
    2. Drive from Columbia Regional Airport (COU) to Sedaliacar car
    5h 40m
    $132–643

  4. Bus, train via Warrensburg

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to Warrensburg Chamber Of Commercebus bus
    3. Take the train from Warrensburg Amtrak Station to Sedalia Amtrak Stationtrain train
    7h 15m
    $71–111

  5. Fly to Kansas City, train

    1. Fly from Des Moines (DSM) to Kansas City (MCI)plane plane DSM - MCI
    2. Take the train from Kansas City to Sedalia Amtrak Stationtrain train
    8h 58m
    $218–986

Des Moines (DSM) to Columbia Regional Airport (COU) flights

Calendar64Weekly Planes
Duration6h 16mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Sedalia.ExpandLaunch map view
  • Distance: 292.6 mi
  • Duration: 6h 57m

What companies run services between Des Moines, IA, USA and Sedalia, MO, USA?

There is no direct connection from Des Moines to Sedalia. However, you can take the bus to Kansas City, walk to On 13Th Between Charlotte & Holmes Wb, take the line 201 bus to On Grand At Pershing Crown Center Shops Sb, walk to Kansas City, then take the train to Sedalia Amtrak Station. Alternatively, you can drive from Des Moines to Sedalia in around 5h 6m.

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