Rome2Rio

How to get fromDes Moines to Seymourby bus, train, car, plane, or bus (Greyhound)

Find Transport to Seymour

See all options

There are 7 ways to get from Des Moines to Seymour by bus, train, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Des Moines to Indianapolisbus bus Btw 1402
    2. Take the bus from Indianapolis to TA Travel Center - Seymourbus bus Indianapolis
    13h 7m
    $156–293

  2. Drive 528.2 mi

    cheapest
    1. Drive from Des Moines to Seymourcar car 528.2 mi
    8h 54m
    $97–140

  3. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis to TA Travel Center - Seymourbus bus
    17h 56m
    $213–461

  4. Fly to Indianapolis, bus

    1. Fly from Des Moines (DSM) to Indianapolis (IND)plane plane DSM - IND
    2. Take the bus from Indianapolis to TA Travel Center - Seymourbus bus
    8h 28m
    $198–918

  5. Bus via Des Moines

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis to TA Travel Center - Seymourbus bus Indianapolis
    13h 17m
    $124–286

  6. Fly to Louisville International Airport, bus

    1. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    2. Take the bus from El Mercadito Grocery - Clarksville, IN to TA Travel Center - Seymourbus bus
    8h 12m
    $206–970

  7. Fly to Nashville, bus

    1. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    2. Take the bus from Tornado Bus Co - Nashville to TA Travel Center - Seymourbus bus
    8h 20m
    $198–798

Des Moines (DSM) to Indianapolis (IND) flights

Calendar112Weekly Planes
Duration5h 23mAverage Duration
Ticket$133Cheapest Price
See schedules

Questions & Answers

Map of how to get from Des Moines to Seymour.ExpandLaunch map view
  • Distance: 545.2 mi
  • Duration: 13h 7m

What companies run services between Des Moines, IA, USA and Seymour, IN, USA?

You can take a bus from Des Moines to Seymour via Indianapolis, Ctc-R, Lafayette Rd & Georgetown Rd, Indianapolis, and TA Travel Center - Seymour in around 13h 7m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers