What is the cheapest way to get from Des Moines to Sikeston?

The cheapest way to get from Des Moines to Sikeston is to drive which costs $80 - $130 and takes 8h 46m.

What is the fastest way to get from Des Moines to Sikeston?

The fastest way to get from Des Moines to Sikeston is to fly and drive which takes 6h 34m and costs $130 - $650.

How far is it from Des Moines to Sikeston?

The distance between Des Moines and Sikeston is 469 miles. The road distance is 461.2 miles.

How do I travel from Des Moines to Sikeston without a car?

The best way to get from Des Moines to Sikeston without a car is to bus and taxi which takes 12h and costs $170 - $280.

How long does it take to get from Des Moines to Sikeston?

It takes approximately 6h 34m to get from Des Moines to Sikeston, including transfers.

Can I drive from Des Moines to Sikeston?

Yes, the driving distance between Des Moines to Sikeston is 461 miles. It takes approximately 8h 46m to drive from Des Moines to Sikeston.

Where can I stay near Sikeston?

There are 13+ hotels available in Sikeston.

Des Moines to Sikeston - 3 ways to travel via plane, car, bus, and taxi

How to get fromDes Moines to Sikeston

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There are 3 ways to get from Des Moines to Sikeston by plane, car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly, drive
best
1. Fly from Des Moines (DSM) to Barkley Regional Airport (PAH)plane DSM - PAH
2. Drive from Barkley Regional Airport (PAH) to Sikestoncar
6h 34m
$138–636
Drive 458.5 mi
cheapest
1. Drive from Des Moines to Sikestoncar 458.5 mi
8h 46m
$84–121
Bus, taxi
1. Take the bus from Des Moines to St Louis Bus Stationbus
2. Take the bus from St Louis Bus Station to Cape Girardeaubus
3. Take the taxi from Cape Girardeau to Sikestontaxi
12h
$175–279

Des Moines (DSM) to Barkley Regional Airport (PAH) flights

21Weekly Planes

6h 26mAverage Duration

$112Cheapest Price

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Questions & Answers

Map of how to get from Des Moines to Sikeston.

Launch map view

Distance: 466.2 mi
Duration: 6h 34m

What companies run services between Des Moines, IA, USA and Sikeston, MO, USA?

There is no direct connection from Des Moines to Sikeston. However, you can take the taxi to Des-Moines-Airport-DSM airport, fly to Barkley Regional Airport (PAH), then drive to Sikeston. Alternatively, you can take the bus to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Sikeston.

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