There are 4 ways to get from Des Moines to Sioux City by bus (Greyhound), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Des Moines to Omaha, NEbus Greyhound US0123S
- Take the bus from Omaha to Sioux Citybus Jefferson Lines 705
4h 55m$52–79Drive 187.8 mi
cheapest- Drive from Des Moines to Sioux Citycar 187.8 mi
3h 36m$35–50Fly to Sioux Gateway Airport/Col. Bud Day Field
- Fly from Des Moines (DSM) to Sioux Gateway Airport/Col. Bud Day Field (SUX)plane DSM - SUX
4h 46m$150–649Fly to Sioux Falls, bus
- Fly from Des Moines (DSM) to Sioux Falls (FSD)plane DSM - FSD
- Take the bus from Sioux Falls to Sioux Citybus
6h 25m$139–636
Des Moines to Sioux City by bus
Comparing Your Travel Options
The cheapest way to get from Des Moines to Sioux City is to drive which costs $30 - $50 and takes 3h 36m.
The fastest way to get from Des Moines to Sioux City is to drive which takes 3h 36m and costs $30 - $50.
No, there is no direct bus from Des Moines to Sioux City. However, there are services departing from Des Moines and arriving at Sioux City via Omaha. The journey, including transfers, takes approximately 4h 55m.
The distance between Des Moines and Sioux City is 233 miles. The road distance is 188.9 miles.
The best way to get from Des Moines to Sioux City without a car is to bus which takes 4h 55m and costs $50 - $80.
It takes approximately 4h 55m to get from Des Moines to Sioux City, including transfers.
Des Moines to Sioux City bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Sioux City is to bus which takes 4h 55m and costs $50 - $80. Alternatively, you can fly, which costs $150 - $650 and takes 4h 46m.
Des Moines to Sioux City bus services, operated by Greyhound USA, arrive at Omaha, NE station.
Yes, the driving distance between Des Moines to Sioux City is 189 miles. It takes approximately 3h 36m to drive from Des Moines to Sioux City.
What companies run services between Des Moines, IA, USA and Sioux City, IA, USA?
You can take a bus from Des Moines to Sioux City via Omaha in around 4h 55m. Alternatively, United Airlines and Southwest Airlines fly from Des Moines (DSM) to Sioux Gateway Airport/Col. Bud Day Field (SUX) twice daily.
- Website
- united.com
Flights from Des Moines to Sioux Gateway Airport/Col. Bud Day Field via Chicago O'Hare
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $110–600
Flights from Des Moines to Sioux Gateway Airport/Col. Bud Day Field via Denver
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $110–600
Flights from Des Moines to Sioux Falls via Denver
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Des Moines to Sioux Falls via Minneapolis
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $80–550
- Website
- aa.com
Flights from Des Moines to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Des Moines to Sioux Falls via Dallas/Ft.Worth
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $160–800
- Website
- allegiantair.com
Flights from Des Moines to Sioux Falls via Nashville
- Ave. Duration
- 4h 31m
- When
- Friday
- Estimated price
- $150–750
Flights from Des Moines to Sioux Falls via Phoenix esa Gateway
- Ave. Duration
- 6h 48m
- When
- Wednesday
- Estimated price
- $240–1,100
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Omaha, NE
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Omaha to Sioux City
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
Bus from Sioux Falls to Sioux City
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- $30–50
- Book at
- Jefferson Lines
- Adult
- $30–50
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Booking & Getting There
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