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How to get fromDes Moines to Sioux Fallsby bus (Greyhound), car, or plane

Find Transport to Sioux Falls

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There are 3 ways to get from Des Moines to Sioux Falls by bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Des Moines to Omaha, NEbus bus Greyhound US0123S
    2. Take the bus from Omaha to Sioux Fallsbus bus Jefferson Lines 705
    7h 14m
    $84–125
  2. Drive  284.2 mi

    cheapest
    1. Drive from Des Moines to Sioux Fallscar car 284.2 mi
    4h 29m
    $52–75
  3. Fly

    1. Fly from Des Moines (DSM) to Sioux Falls (FSD)plane plane DSM - FSD
    4h 49m
    $91–465

Des Moines (DSM) to Sioux Falls (FSD) flights

Calendar126Weekly Planes
Duration5h 30mAverage Duration
Ticket$72Cheapest Price
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Comparing Your Travel Options

What companies run services between Des Moines, IA, USA and Sioux Falls, SD, USA?

You can take a bus from Des Moines to Sioux Falls via Omaha and Sioux Falls in around 7h 14m. Alternatively, Delta, United Airlines, and two other airlines fly from Des Moines (DSM) to Sioux Falls (FSD) hourly.

Airlines
Bus operators

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