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How to get fromDes Moines to Southern Illinois University Carbondaleby plane, car, bus, train, or bus (Greyhound, Amtrak, Flixbus)

Find Transport to Southern Illinois University Carbondale

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There are 5 ways to get from Des Moines to Southern Illinois University Carbondale by plane, car, bus, train, or bus (Greyhound, Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barkley Regional Airport, drive

    best
    1. Fly from Des Moines (DSM) to Barkley Regional Airport (PAH)plane plane DSM - PAH
    2. Drive from Barkley Regional Airport (PAH) to Southern Illinois University Carbondalecar car
    6h 49m
    $119–589

  2. Bus

    cheapest
    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    11h 41m
    $76–162

  3. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus Greyhound US0157S
    2. Take the train from Champaign-Urbana to Carbondaletrain train City of New Orleans / ...
    11h 40m
    $106–217

  4. Drive 423.5 mi

    1. Drive from Des Moines to Southern Illinois University Carbondalecar car 423.5 mi
    8h 43m
    $78–112

  5. Fly to Williamson County Regional Airport

    1. Fly from Des Moines (DSM) to Williamson County Regional Airport (MWA)plane plane DSM - MWA
    4h 27m
    $143–566

Des Moines (DSM) to Barkley Regional Airport (PAH) flights

Calendar21Weekly Planes
Duration6h 26mAverage Duration
Ticket$94Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Southern Illinois University Carbondale.ExpandLaunch map view
  • Distance: 476.5 mi
  • Duration: 6h 49m

What companies run services between Des Moines, IA, USA and Southern Illinois University Carbondale, IL, USA?

United Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Williamson County Regional Airport (MWA) 3 times a day. Alternatively, you can take a bus from Des Moines to Southern Illinois University Carbondale via St Louis Bus Station, St. Louis, and Carbondale in around 11h 41m.

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