Rome2Rio

How to get fromDes Moines to St. Petersburgby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Flixbus)

Find Transport to St. Petersburg

See all options

There are 8 ways to get from Des Moines to St. Petersburg by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Sarasota–Bradenton International Airport

    best
    1. Fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ)plane plane DSM - SRQ
    5h 49m
    $250–1,131

  2. Fly to Saint Petersburg–Clearwater International Airport

    cheapest
    1. Fly from Des Moines (DSM) to Saint Petersburg–Clearwater International Airport (PIE)plane plane DSM - PIE
    4h 48m
    $184–777

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Marion Transit Parking Lot to 2Nd Ave Ne + Beach Drivebus bus 100
    32h 22m
    $232–430

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus Btw 1202 / ...
    2. Take the train from Chicago Union Station to Tampatrain train Floridian
    2d 2h

  5. Drive 1,345.8 mi

    1. Drive from Des Moines to St. Petersburgcar car 1,345.8 mi
    24h
    $246–355

  6. Fly to Tampa

    1. Fly from Des Moines (DSM) to Tampa (TPA)plane plane DSM - TPA
    8h
    $194–827

  7. Fly to Orlando Sanford, drive

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to St. Petersburgcar car
    5h 23m
    $201–806

  8. Bus via Champaign

    1. Take the bus from Des Moines to Champaignbus bus
    2. Take the bus from Champaign Intermodal Trans Ctr to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    34h 58m

Des Moines to St. Petersburg by bus

Calendar7Weekly Buses
Duration32h 22mAverage Duration
Ticket$232Cheapest Price
See schedules

Questions & Answers

Map of how to get from Des Moines to St. Petersburg.ExpandLaunch map view
  • Distance: 1,204.4 mi
  • Duration: 5h 49m

What companies run services between Des Moines, IA, USA and St. Petersburg, FL, USA?

Allegiant Air, Delta, and three other airlines fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ) 5 times a day. Alternatively, you can take a bus from Des Moines to Grand Central Station - E via St Louis Bus Station, Atlanta Bus Station, Tampa Bus Station, Marion Transit Parking Lot, and 2Nd Ave Ne + Beach Drive in around 32h 22m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers