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How to get fromDes Moines to Tennesseeby plane, bus, train, car, bus (Greyhound, Amtrak), or bus (Greyhound)

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There are 9 ways to get from Des Moines to Tennessee by plane, bus, train, car, bus (Greyhound, Amtrak), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Nashville

    best
    1. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    2h 35m
    $111–575

  2. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Carbondaletrain train
    3. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    16h 4m
    $124–244

  3. Bus, train via Chicago

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Carbondaletrain train
    4. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    19h 50m
    $177–376

  4. Drive  624.9 mi

    1. Drive from Des Moines to Nashvillecar car 624.9 mi
    12h 4m
    $114–165

  5. Fly to Mcghee Tyson Airport

    1. Fly from Des Moines (DSM) to Mcghee Tyson Airport (TYS)plane plane DSM - TYS
    4h 43m
    $294–1,293

  6. Fly to Chattanooga Metropolitan Airport

    1. Fly from Des Moines (DSM) to Chattanooga Metropolitan Airport (CHA)plane plane DSM - CHA
    4h 26m
    $135–592

  7. Fly to Memphis

    1. Fly from Des Moines (DSM) to Memphis (MEM)plane plane DSM - MEM
    6h 11m
    $210–1,124

  8. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Nashville Bus Stationbus bus Greyhound US0100 / ...
    16h 8m
    $120–175

  9. Bus via Speedway

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis to Tornado Bus Co - Nashvillebus bus Indianapolis
    18h 8m
    $137–202

Des Moines to Tennessee by bus and train

Calendar5Weekly Services
Duration16h 4mAverage Duration
Ticket$124Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Tennessee.ExpandLaunch map view
  • Distance: 546.8 mi
  • Duration: 2h 35m

What companies run services between Des Moines, IA, USA and Tennessee, USA?

Allegiant Air and Southwest Airlines fly from Des Moines (DSM) to Nashville (BNA) once daily. Alternatively, you can take a bus from Des Moines to Central 5Th Ave - Bay 4 via Indianapolis Union Station, Nashville Bus Station, and Lafayette St & 5Th Ave S Wb in around 16h 8m.

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