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How to get fromDes Moines to West Chesterby plane, bus, train, bus (Greyhound), car, taxi, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Des Moines to West Chester by plane, bus, train, bus (Greyhound), car, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Philadelphia International Airport, line 104 bus

    best
    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane plane DSM - PHL
    2. Take the bus from 69th St TC West Trolley Platform to Chestnut St & Darlington Stbus bus
    4h 49m
    $167–730

  2. Fly to Newark Liberty International Airport, train

    cheapest
    1. Fly from Des Moines (DSM) to Newark Liberty International Airport (EWR)plane plane DSM - EWR
    2. Take the train from Newark Liberty International Airport to 30th Street Stationtrain train
    6h 33m
    $144–577

  3. Bus, train via Pittsburgh

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    4. Take the train from Pittsburgh Amtrak Station to Paoli Amtrak Stationtrain train
    28h 21m
    $280–619

  4. Bus (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to King of Prussia Park & Ridebus bus Greyhound US0421
    28h 46m
    $179–280

  5. Drive  1,049.8 mi

    1. Drive from Des Moines to West Chestercar car 1,049.8 mi
    17h 16m
    $192–277

  6. Fly to Lancaster, taxi

    1. Fly from Des Moines (DSM) to Lancaster (LNS)plane plane DSM - LNS
    2. Take the taxi from Lancaster-Airport-LNS to West Chestertaxi taxi
    5h 54m
    $318–861

  7. Fly to Laguardia Airport, train

    1. Fly from Des Moines (DSM) to Laguardia Airport (LGA)plane plane DSM - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    6h 54m
    $217–1,483

  8. Fly to Ronald Reagan Washington National Airport, train

    1. Fly from Des Moines (DSM) to Ronald Reagan Washington National Airport (DCA)plane plane DSM - DCA
    2. Take the train from Washington Union Station to 30th Street Stationtrain train
    6h 43m
    $223–964

  9. Bus via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago Bus Station to Philadelphia Bus Stationbus bus FlixBus N2642
    29h 52m
    $198–298

  10. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to 30th Street Stationtrain train Cardinal
    35h 43m
    $328–738

Des Moines to West Chester by bus and train

Calendar7Weekly Services
Duration28h 21mAverage Duration
Ticket$280Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to West Chester.ExpandLaunch map view
  • Distance: 1,008.5 mi
  • Duration: 4h 49m

What companies run services between Des Moines, IA, USA and West Chester, PA, USA?

You can take a bus from Des Moines to Chestnut St & Church St via Indianapolis Union Station, King of Prussia Park & Ride, South Gulph Rd & Bill Smith Blvd, and Plaza at King of Prussia in around 28h 46m.

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