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How to get fromDes Moines to Wilmingtonby plane, bus (Greyhound, Flixbus), car, taxi, or bus (Greyhound)

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There are 5 ways to get from Des Moines to Wilmington by plane, bus (Greyhound, Flixbus), car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Wilmington International Airport

    best
    1. Fly from Des Moines (DSM) to Wilmington International Airport (ILM)plane plane DSM - ILM
    4h 50m
    $162–688

  2. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    4. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    34h 12m
    $209–412

  3. Drive 1,179.1 mi

    1. Drive from Des Moines to Wilmingtoncar car 1,179.1 mi
    20h 53m
    $216–311

  4. Fly to Albert J. Ellis Airport, taxi

    1. Fly from Des Moines (DSM) to Albert J. Ellis Airport (OAJ)plane plane DSM - OAJ
    2. Take the taxi from Albert J. Ellis Airport (OAJ) to Wilmingtontaxi taxi
    5h 55m
    $268–831

  5. Bus via Indianapolis (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    4. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    35h 9m
    $216–425

Des Moines to Wilmington by bus

Calendar7Weekly Buses
Duration34h 12mAverage Duration
Ticket$209Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Wilmington.ExpandLaunch map view
  • Distance: 1,003.4 mi
  • Duration: 4h 50m

What companies run services between Des Moines, IA, USA and Wilmington, NC, USA?

American Airlines, Delta, and United Airlines fly from Des Moines (DSM) to Wilmington International Airport (ILM) every 3 hours. Alternatively, you can take a bus from Des Moines to Market St WB at 4th St via St Louis Bus Station, Atlanta Bus Station, Myrtle Beach Bus Station, and Forden Station in around 34h 12m.

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