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How to get fromDes Moines to Worcesterby plane, bus, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

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There are 10 ways to get from Des Moines to Worcester by plane, bus, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Boston Logan Airport, bus

    best
    1. Fly from Des Moines (DSM) to Boston Logan Airport (BOS)plane plane DSM - BOS
    2. Take the bus from Boston to Worcesterbus bus
    5h 6m
    $175–747

  2. Fly to Theodore Francis Green State Airport, bus

    cheapest
    1. Fly from Des Moines (DSM) to Theodore Francis Green State Airport (PVD)plane plane DSM - PVD
    2. Take the bus from Providence to Worcester Union Stationbus bus
    8h 9m
    $152–597

  3. Bus

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the bus from Chicago Bus Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Worcester Union Stationbus bus
    28h 15m

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus Btw 1202 / ...
    2. Take the train from Chicago Union Station to Worcester Union Stationtrain train Lake Shore Limited
    28h 19m

  5. Drive 1,258.4 mi

    1. Drive from Des Moines to Worcestercar car 1,258.4 mi
    21h 22m
    $230–332

  6. Fly to Worcester Regional Airport

    1. Fly from Des Moines (DSM) to Worcester Regional Airport (ORH)plane plane DSM - ORH
    10h 21m
    $190–773

  7. Fly to Bradley International Airport, bus

    1. Fly from Des Moines (DSM) to Bradley International Airport (BDL)plane plane DSM - BDL
    2. Take the bus from Hartford to Worcesterbus bus
    7h 40m
    $182–810

  8. Fly to Manchester Airport, bus

    1. Fly from Des Moines (DSM) to Manchester Airport (MHT)plane plane DSM - MHT
    2. Take the bus from Boston Manchester Airport to Bostonbus bus
    3. Take the bus from Boston to Worcesterbus bus
    8h 53m
    $191–809

  9. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Worcester Union Stationtrain train
    30h 25m

  10. Bus via Indianapolis

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Worcesterbus bus
    33h 55m
    $226–469

Des Moines (DSM) to Boston Logan Airport (BOS) flights

Calendar68Weekly Planes
Duration4h 59mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Worcester.ExpandLaunch map view
  • Distance: 1,216.1 mi
  • Duration: 5h 6m

What companies run services between Des Moines, IA, USA and Worcester, MA, USA?

You can take a bus from Des Moines to Worcester Union Station via Chicago Bus Station and Newark Penn Station in around 28h 15m. Alternatively, Delta and American Airlines fly from Des Moines (DSM) to Worcester Regional Airport (ORH) 4 times a day.

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