There are 7 ways to get from Des Moines to Zacatecas by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Zacatecas International Airport
best- Fly from Des Moines (DSM) to Zacatecas International Airport (ZCL)plane DSM - ZCL
7h 5m$5,357–22,072Fly to San Luis Potosí Airport, bus
cheapest- Fly from Des Moines (DSM) to San Luis Potosí Airport (SLP)plane DSM - SLP
- Take the bus from San Luis Potosí to Zacatecasbus
10h 11m$5,007–20,512Bus via Dallas
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to Dallas Bus Stationbus
- Take the bus from Tornado Bus Co - Dallas I-30 to Zacatecasbus
37h 37m$6,077–7,540Bus, train
- Take the bus from Des Moines to Bloomington-Normalbus
- Take the train from Bloomington-Normal to San Marcos Amtraktrain
- Take the bus from San Marcos to Zacatecasbus
2d 2h$8,165–18,938Drive 2,457.5 km
- Drive from Des Moines to Zacatecascar 2,457.5 km
25h 46m$5,119–7,395Fly to Lic. Jesús Terán Peredo International Airport, bus
- Fly from Des Moines (DSM) to Lic. Jesús Terán Peredo International Airport (AGU)plane DSM - AGU
- Take the bus from Aguascalientes to Zacatecasbus
8h 29m$5,077–21,152Bus
- Take the bus from Des Moines to Omaha, NEbus Greyhound US0123S
- Take the bus from Omaha to Zacatecasbus Omaha-Aguascalientes
38h 20m$5,623–6,445
Des Moines to Zacatecas by bus and tram
Comparing Your Travel Options
The cheapest way to get from Des Moines to Zacatecas is to bus which costs $5500 - $6500 and takes 38h 20m.
The fastest way to get from Des Moines to Zacatecas is to fly which takes 7h 5m and costs $5000 - $23000.
No, there is no direct bus from Des Moines to Zacatecas. However, there are services departing from Des Moines and arriving at Zacatecas via Kansas City Bus Station, Gaston @ Good Latimer - N - Ns and Tornado Bus Co - Dallas I-30. The journey, including transfers, takes approximately 37h 37m.
The distance between Des Moines and Zacatecas is 2271 km. The road distance is 2457.5 km.
The best way to get from Des Moines to Zacatecas without a car is to bus via Dallas which takes 37h 37m and costs $6000 - $8000.
It takes approximately 7h 5m to get from Des Moines to Zacatecas, including transfers.
Des Moines to Zacatecas bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Des Moines to Zacatecas is to fly which takes 7h 5m and costs $5000 - $23000. Alternatively, you can bus via Dallas, which costs $6000 - $8000 and takes 37h 37m.
Des Moines to Zacatecas bus services, operated by Jefferson Lines, arrive at Kansas City station.
Zacatecas is 1h behind Des Moines. It is currently 1:50 AM in Des Moines and 12:50 AM in Zacatecas.
What companies run services between Des Moines, IA, USA and Zacatecas, Mexico?
American Airlines flies from Des Moines (DSM) to Zacatecas International Airport (ZCL) once daily. Alternatively, you can take a bus from Des Moines to Zacatecas via Kansas City, Kansas City Bus Station, Dallas Bus Station, Bachman Station, Deep Ellum Station, Gaston @ Good Latimer - N - Ns, Samuell @ Cinnabar - E - Ns, and Tornado Bus Co - Dallas I-30 in around 37h 37m.
- Website
- volaris.com
Flights from Des Moines to Lic. Jesús Terán Peredo International Airport via Chicago Midway
- Ave. Duration
- 6h 46m
- When
- Tuesday
- Estimated price
- $8,000–25,000
Flights from Des Moines to San Luis Potosí Airport via Chicago Midway
- Ave. Duration
- 7h 8m
- When
- Sunday, Thursday, and Tuesday
- Estimated price
- $7,500–24,000
Flights from Des Moines to San Luis Potosí Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 19m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $6,500–22,000
Flights from Des Moines to San Luis Potosí Airport via Houston
- Ave. Duration
- 8h 34m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $4,100–19,000
- Website
- aa.com
Flights from Des Moines to Zacatecas International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $4,500–21,000
Flights from Des Moines to Lic. Jesús Terán Peredo International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $4,300–20,000
Flights from Des Moines to San Luis Potosí Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $4,000–19,000
- Website
- united.com
Flights from Des Moines to Lic. Jesús Terán Peredo International Airport via Houston
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $4,400–21,000
Flights from Des Moines to San Luis Potosí Airport via Houston
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $4,100–19,000
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Bloomington-Normal to San Marcos Amtrak
- Ave. Duration
- 27h 46m
- Frequency
- Once daily
- Estimated price
- $5,500–15,000
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $950–1,400
- Book at
- Jefferson Lines
- Adult
- $950–1,400
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Kansas City Bus Station to Dallas Bus Station
- Ave. Duration
- 12h 15m
- Frequency
- Twice daily
- Estimated price
- $1,600–2,600
- Website
- Greyhound
Bus from Des Moines to Bloomington-Normal
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $850–1,400
- Website
- Greyhound
Bus from Des Moines to Omaha, NE
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $400–650
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Kansas City Bus Station to Dallas Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- 6 times a week
- Estimated price
- $1,500–2,400
- Schedules at
- Flixbus USA
- Phone
- +52 81 2152 6736
- [email protected]
- Website
- Tornado Bus Company
Bus from Tornado Bus Co - Dallas I-30 to Zacatecas
- Ave. Duration
- 18h 35m
- Frequency
- Once daily
- Estimated price
- $3,497
- Website
- Tornado Bus Company
- Phone
- +1 800 923 1799
- [email protected]
- Website
- Omnibus Express (OMEX VIP)
Bus from San Marcos to Zacatecas
- Ave. Duration
- 14h 13m
- Frequency
- Once daily
- Estimated price
- $1,800–2,600
- Schedules at
- Omnibus Express (OMEX VIP)
- Phone
- +52 55 2643 9028
- Website
- apoloplatinum.com.mx
Bus from Aguascalientes to Zacatecas
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $320–600
- Schedules at
- platinumline.mx
- Book at
- platinumline.mx
- Ejecutivo
- $420–470
- Confort
- $500–600
- Primera Clase
- $320–470
- Phone
- +52 55 5141 4300
- [email protected]
- Website
- odm.com.mx
Bus from San Luis Potosí to Zacatecas
- Ave. Duration
- 2h 55m
- Frequency
- Every 2 hours
- Estimated price
- $500–900
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 449 291 3048
- [email protected]
- Website
- TL Premium
Bus from Omaha to Zacatecas
- Ave. Duration
- 34h 30m
- Frequency
- Twice a week
- Estimated price
- $5,200–5,800
- Schedules at
- TL Premium
Want to know more about travelling around Mexico
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Yes, the driving distance between Des Moines to Zacatecas is 2458 km. It takes approximately 25h 46m to drive from Des Moines to Zacatecas.
There are 62+ hotels available in Zacatecas.






























