There are 6 ways to get from Des Plaines to Cincinnati by plane, bus (Flixbus), car, train, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Covington
best- Fly from Chicago O'Hare International Airport (ORD) to Covington (CVG)plane ORD - CVG
3h 22m$152–802Bus (Flixbus)
cheapest- Take the bus from Chicago Bus Station to Cincinnatibus FlixBus 2514 / ...
7h 35m$47–78Drive 303.4 mi
- Drive from Des Plaines to Cincinnaticar 303.4 mi
5h 27m$56–80Fly Chicago O'Hare International Airport to Blue Grass Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane ORD - LEX
- Drive from Lexington-Airport-LEX to Cincinnaticar
4h 21m$55–303Train, subway to Chicago Midway International Airport, fly to Covington
- Take the train from Des Plaines to Chicago OTCtrain
- Take the subway from Clark/Lake to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Covington (CVG)plane MDW - CVG
4h 42m$158–372Fly Chicago O'Hare International Airport to Louisville International Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane ORD - SDF
- Drive from Louisville-Airport-SDF to Cincinnaticar
4h 33m$89–488
Des Plaines to Cincinnati by train and bus (Flixbus)
Comparing Your Travel Options
The cheapest way to get from Des Plaines to Cincinnati is to bus which costs $45 - $80 and takes 7h 35m.
The fastest way to get from Des Plaines to Cincinnati is to fly which takes 3h 22m and costs $150 - $800.
No, there is no direct bus from Des Plaines to Cincinnati. However, there are services departing from Madison & Canal and arriving at Cincinnati via Chicago Bus Station. The journey, including transfers, takes approximately 7h 35m.
The distance between Des Plaines and Cincinnati is 283 miles. The road distance is 305.2 miles.
The best way to get from Des Plaines to Cincinnati without a car is to bus which takes 7h 35m and costs $45 - $80.
It takes approximately 3h 22m to get from Des Plaines to Cincinnati, including transfers.
Des Plaines to Cincinnati bus services, operated by Flixbus USA, depart from Chicago Bus Station.
The best way to get from Des Plaines to Cincinnati is to fly which takes 3h 22m and costs $150 - $800. Alternatively, you can bus, which costs $45 - $80 and takes 7h 35m.
Des Plaines to Cincinnati bus services, operated by Flixbus USA, arrive at Cincinnati station.
Cincinnati is 1h ahead of Des Plaines. It is currently 7:40 PM in Des Plaines and 8:40 PM in Cincinnati.
What companies run services between Des Plaines, IL, USA and Cincinnati, OH, USA?
American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Covington (CVG) hourly. Alternatively, Flixbus USA operates a bus from Chicago Bus Station to Cincinnati twice daily. Tickets cost $40–70 and the journey takes 5h 45m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Covington
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $65–440
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $40–280
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $70–460
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Covington
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $65–440
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $40–280
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $70–460
- Website
- southwest.com
Flights from Chicago Midway International Airport to Covington
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $90–650
- Phone
- +1 312-696-3872
- Website
- Metra
Train from Des Plaines to Chicago OTC
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- $4–5
- Website
- Metra
- Adult
- $4–5
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Clark/Lake to Midway
- Ave. Duration
- 27 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Cincinnati
- Ave. Duration
- 5h 45m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Des Plaines to Cincinnati is 305 miles. It takes approximately 5h 27m to drive from Des Plaines to Cincinnati.
There are 668+ hotels available in Cincinnati.