There are 5 ways to get from Des Plaines to Des Moines by plane, bus (Greyhound), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Chicago O'Hare International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
2h 49m$58–283Drive 320.8 mi
cheapest- Drive from Des Plaines to Des Moinescar 320.8 mi
5h 43m$55–80Bus (Greyhound)
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0155S / ...
10h 15m$72–108Train to Chicago Midway International Airport, fly
- Take the train from Des Plaines to Chicago OTCtrain
- Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane MDW - DSM
4h 9m$89–463Train, bus
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain Southwest Chief / ...
- Take the bus from Galesburg to Des Moinesbus Greyhound US0157S
10h 15m$127–208
Des Plaines to Des Moines by train and bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Des Plaines to Des Moines is to drive which costs $55 - $80 and takes 5h 43m.
The fastest way to get from Des Plaines to Des Moines is to fly which takes 2h 49m and costs $55 - $290.
No, there is no direct bus from Des Plaines to Des Moines. However, there are services departing from Madison & Canal and arriving at Des Moines via Chicago Bus Station. The journey, including transfers, takes approximately 10h 15m.
The distance between Des Plaines and Des Moines is 309 miles. The road distance is 322.7 miles.
The best way to get from Des Plaines to Des Moines without a car is to bus which takes 10h 15m and costs $70 - $110.
It takes approximately 2h 49m to get from Des Plaines to Des Moines, including transfers.
Des Plaines to Des Moines bus services, operated by Greyhound USA, depart from Chicago Bus Station.
The best way to get from Des Plaines to Des Moines is to fly which takes 2h 49m and costs $55 - $290. Alternatively, you can bus, which costs $70 - $110 and takes 10h 15m.
Des Plaines to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Yes, the driving distance between Des Plaines to Des Moines is 323 miles. It takes approximately 5h 43m to drive from Des Plaines to Des Moines.
What companies run services between Des Plaines, IL, USA and Des Moines, IA, USA?
American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 2 hours. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Des Moines 5 times a day. Tickets cost $65–100 and the journey takes 8h 25m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $40–260
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $40–260
- Website
- southwest.com
Flights from Chicago Midway International Airport to Des Moines
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $65–430
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Des Moines via Minneapolis
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $50–300
- Phone
- +1 312-696-3872
- Website
- Metra
Train from Des Plaines to Chicago OTC
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- $4–5
- Website
- Metra
- Adult
- $4–5
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a day
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
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Booking & Getting There
There are 241+ hotels available in Des Moines.










