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How to get fromDes Plaines to Des Moinesby plane, bus (Greyhound), car, train, or bus

Find Transport to Des Moines

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There are 5 ways to get from Des Plaines to Des Moines by plane, bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane plane ORD - DSM
    2h 49m
    $58–283
  2. Drive  320.8 mi

    cheapest
    1. Drive from Des Plaines to Des Moinescar car 320.8 mi
    5h 43m
    $55–80
  3. Bus (Greyhound)

    1. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S / ...
    10h 15m
    $72–108
  4. Train to Chicago Midway International Airport, fly

    1. Take the train from Des Plaines to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane plane MDW - DSM
    4h 9m
    $89–463
  5. Train, bus

    1. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train Southwest Chief / ...
    2. Take the bus from Galesburg to Des Moinesbus bus Greyhound US0157S
    10h 15m
    $127–208

Des Plaines to Des Moines by train and bus (Greyhound)

Calendar36Weekly Services
Duration10h 15mAverage Duration
Ticket$72Cheapest Price
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Comparing Your Travel Options

What companies run services between Des Plaines, IL, USA and Des Moines, IA, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 2 hours. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Des Moines 5 times a day. Tickets cost $65–100 and the journey takes 8h 25m.

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