There are 6 ways to get from Des Plaines to Indianapolis by bus (Greyhound), train (Amtrak), car, plane, bus (Flixbus), train, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Chicago Bus Station to Indianapolis Union Stationbus Greyhound US0100 / ...
4h 54m$36–63Bus via Jefferson Park Transit Center (Flixbus)
cheapest- Take the bus from Chicago Bus Station to Indianapolisbus FlixBus 2511 / ...
6h 46m$34–56Train (Amtrak)
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
6h 37m$67–138Drive 196.6 mi
- Drive from Des Plaines to Indianapoliscar 196.6 mi
3h 36m$36–52Fly from Chicago O'Hare International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Indianapolis (IND)plane ORD - IND
3h 24m$422–1,302Train, subway to Chicago Midway International Airport, fly
- Take the train from Des Plaines to Chicago OTCtrain
- Take the subway from Clark/Lake to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Indianapolis (IND)plane MDW - IND
4h 43m$73–502
Des Plaines to Indianapolis by train and bus (Greyhound)
Questions & Answers
The cheapest way to get from Des Plaines to Indianapolis is to bus via Jefferson Park Transit Center which costs $30 - $60 and takes 6h 46m.
The fastest way to get from Des Plaines to Indianapolis is to fly which takes 3h 24m and costs $420 - $1,300.
No, there is no direct bus from Des Plaines to Indianapolis station. However, there are services departing from Madison & Canal and arriving at Indianapolis Union Station via Chicago Bus Station. The journey, including transfers, takes approximately 4h 54m.
No, there is no direct train from Des Plaines to Indianapolis. However, there are services departing from Des Plaines and arriving at Indianapolis via Chicago Union Station. The journey, including transfers, takes approximately 6h 37m.
The distance between Des Plaines and Indianapolis is 199 miles. The road distance is 197.7 miles.
The best way to get from Des Plaines to Indianapolis without a car is to bus which takes 4h 54m and costs $35 - $65.
It takes approximately 4h 54m to get from Des Plaines to Indianapolis, including transfers.
Des Plaines to Indianapolis bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Des Plaines to Indianapolis train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Des Plaines to Indianapolis is to bus which takes 4h 54m and costs $35 - $65. Alternatively, you can train, which costs $65 - $140 and takes 6h 37m, you could also fly, which costs $420 - $1,300 and takes 3h 24m.
What companies run services between Des Plaines, IL, USA and Indianapolis, IN, USA?
Greyhound USA operates a bus from Chicago Bus Station to Indianapolis Union Station 5 times a day. Tickets cost $29–55 and the journey takes 3h 5m. Alternatively, Amtrak operates a train from Chicago Union Station to Indianapolis 3 times a week. Tickets cost $60–130 and the journey takes 4h 54m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Indianapolis
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $55–380
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Indianapolis
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $55–380
- Website
- southwest.com
Flights from Chicago Midway International Airport to Indianapolis
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $65–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 312-696-3872
- Website
- metra.com
Train from Des Plaines to Chicago OTC
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- $4–5
- Website
- https://metra.com
- Adult
- $4–5
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Clark/Lake to Midway
- Ave. Duration
- 27 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Chicago Bus Station to Indianapolis Union Station
- Ave. Duration
- 3h 5m
- Frequency
- 5 times a day
- Estimated price
- $29–55
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago Bus Station to Indianapolis
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- $29–50
- Schedules at
- flixbus.com
Want to know more about travelling around United States
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More Questions & Answers
Des Plaines to Indianapolis bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Indianapolis is 1h ahead of Des Plaines. It is currently 9:54 AM in Des Plaines and 10:54 AM in Indianapolis.
Des Plaines to Indianapolis train services, operated by Amtrak, arrive at Indianapolis station.
Yes, the driving distance between Des Plaines to Indianapolis is 198 miles. It takes approximately 3h 36m to drive from Des Plaines to Indianapolis.
There are 797+ hotels available in Indianapolis.












