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How to get fromDes Plaines to Kentuckyby plane, bus (Greyhound, Flixbus), train, bus, car, subway, or bus (Amtrak)

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There are 11 ways to get from Des Plaines to Kentucky by plane, bus (Greyhound, Flixbus), train, bus, car, subway, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Covington

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Covington (CVG)plane plane ORD - CVG
    3h 17m
    $152–802

  2. Fly Chicago O'Hare International Airport to Blue Grass Airport, line 3 bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Take the bus from Transit Center to Centre Parkway @ 1349bus bus
    5h 5m
    $42–292

  3. Bus

    1. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    7h 54m
    $47–98

  4. Train, bus via Indianapolis

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    9h 27m
    $79–173

  5. Drive  311.3 mi

    1. Drive from Des Plaines to Louisvillecar car 311.3 mi
    5h 28m
    $57–83

  6. Fly Chicago O'Hare International Airport to Owensboro–Daviess County Regional Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Owensboro–Daviess County Regional Airport (OWB)plane plane ORD - OWB
    2h 52m
    $91–223

  7. Fly Chicago O'Hare International Airport to Louisville International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    3h 57m
    $66–443

  8. Train, subway to Chicago Midway International Airport, fly to Covington

    1. Take the train from Des Plaines to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Covington (CVG)plane plane MDW - CVG
    4h 42m
    $158–372

  9. Train, subway to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Des Plaines to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    5h 7m
    $92–613

  10. Train, bus

    1. Take the train from Millennium Station to Gary Metro Centertrain train Ssl / ...
    2. Take the bus from Gary Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    8h 19m
    $54–97

  11. Bus via Lafayette

    1. Take the bus from O'Hare Multi-Modal Facility to Quality Inn - Purduebus bus Ord
    2. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus Chicago
    12h 4m
    $88–128

Des Plaines to Kentucky by train and bus

Calendar40Weekly Services
Duration7h 54mAverage Duration
Ticket$47Cheapest Price
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Questions & Answers

Map of how to get from Des Plaines to Kentucky.ExpandLaunch map view
  • Distance: 280.9 mi
  • Duration: 3h 17m

What companies run services between Des Plaines, IL, USA and Kentucky, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Covington (CVG) hourly. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Louisville Bus Station 4 times a day. Tickets cost $45–90 and the journey takes 6h 5m. Flixbus USA also services this route twice daily.

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