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How to get fromDes Plaines to Mississaugaby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Flixbus)

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There are 7 ways to get from Des Plaines to Mississauga by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Toronto Pearson International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Toronto Pearson International Airport (YYZ)plane plane ORD - YYZ
    4h 22m
    $504–1,406

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Detroit Bus Stationbus bus Greyhound US0160
    2. Take the bus from Detroit Bus Station to Mississaugabus bus FlixBus N2706
    14h 55m
    $120–196

  3. Train

    1. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    2. Take the train from Buffalo to Oakvilletrain train VIA Rail
    17h 45m
    $455–903

  4. Drive  823.6 km

    1. Drive from Des Plaines to Mississaugacar car 823.6 km
    8h 42m
    $165–238

  5. Fly to Buffalo Niagara International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    2. Take the bus from Buffalo to Mississaugabus bus
    6h 49m
    $273–506

  6. Fly to Toronto Island Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Toronto Island Airport (YTZ)plane plane ORD - YTZ
    2. Take the train from Union Station GO to Erindale GOtrain train
    5h 48m
    $287–2,009

  7. Bus via Milwaukee Airport (MKE)

    1. Take the bus from Multi-Modal/Rental Car Facility to Mitchell Airportbus bus
    2. Take the bus from Milwaukee Mitchell Airport to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Mississaugabus bus
    16h 15m
    $179–258

Des Plaines to Mississauga by train and bus

Calendar5Weekly Services
Duration14h 55mAverage Duration
Ticket$120Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Plaines to Mississauga.ExpandLaunch map view
  • Distance: 721.4 km
  • Duration: 4h 22m

What companies run services between Des Plaines, IL, USA and Mississauga, ON, Canada?

American Airlines, Air Canada, and United Airlines fly from Chicago O'Hare International Airport (ORD) to Toronto Pearson International Airport (YYZ) hourly. Alternatively, you can take a train from Des Plaines to Mississauga via Chicago OTC, Madison & Canal, Harrison & Jefferson, Chicago Bus Station, and Detroit Bus Station in around 14h 55m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Canada

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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Need to know: Greyhound

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