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How to get fromDes Plaines to Niagara Fallsby plane, bus, train (Amtrak), car, train, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Des Plaines to Niagara Falls by plane, bus, train (Amtrak), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Buffalo Niagara International Airport, bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    4h 39m
    $174–308

  2. Bus

    cheapest
    1. Take the bus from Chicago to Clevelandbus bus Bsb 26
    2. Take the bus from Cleveland to Buffalobus bus Bsb 10
    15h 31m
    $58–151

  3. Train

    1. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    2. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train Empire Service / ...
    14h 8m
    $305–608

  4. Drive  534.4 mi

    1. Drive from Des Plaines to Niagara Fallscar car 534.4 mi
    9h 8m
    $98–141

  5. Fly Chicago Midway International Airport to Buffalo Niagara International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    5h 57m
    $170–328

  6. Fly Chicago O'Hare International Airport to Rochester, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)plane plane ORD - ROC
    2. Take the train from Rochester to Niagara Falls Amtrak Stationtrain train
    6h 14m
    $143–792

  7. Fly Chicago O'Hare International Airport to Toronto Pearson International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Toronto Pearson International Airport (YYZ)plane plane ORD - YYZ
    2. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    6h 31m
    $404–1,065

  8. Fly Chicago O'Hare International Airport to Toronto Island Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Toronto Island Airport (YTZ)plane plane ORD - YTZ
    2. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    6h 18m
    $208–1,456

  9. Bus via Detroit

    1. Take the bus from Chicago Bus Station to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Torontobus bus
    3. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    17h 35m
    $90–199

Des Plaines to Niagara Falls by train and bus

Calendar14Weekly Services
Duration14h 8mAverage Duration
Ticket$305Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Plaines to Niagara Falls.ExpandLaunch map view
  • Distance: 506.2 mi
  • Duration: 4h 39m

What companies run services between Des Plaines, IL, USA and Niagara Falls, NY, USA?

You can take a train from Des Plaines to Niagara Falls Amtrak Station via Chicago OTC, Madison & Canal, Clinton & Jackson, Chicago Union Station, and Buffalo Depew Station in around 14h 8m. Alternatively, you can take a bus from Busse Hwy & Mason Ln to Main Street & Pine Avenue via Jefferson Park Transit Center - Bus Stop C, Jefferson Park Transit Center, Washington & Canal, Madison & Canal, Harrison & Jefferson, Chicago, Cleveland, and Ellicott Street & MTC Static in around 15h 31m.

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