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How to get fromDes Plaines to North Carolinaby plane, bus, train (Amtrak), car, train, subway, or bus (Amtrak, Greyhound)

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There are 10 ways to get from Des Plaines to North Carolina by plane, bus, train (Amtrak), car, train, subway, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    3h 25m
    $128–635

  2. Bus via Hurricane

    cheapest
    1. Take the bus from Chicago to Columbus - Mound Stbus bus
    2. Take the bus from Columbus - Mound St to Hurricanebus bus
    3. Take the bus from Hurricane to Charlotte Bus Stationbus bus
    21h 24m
    $80–218

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Carytrain train Floridian
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train Piedmont / ...
    30h 34m
    $400–871

  4. Drive 746.2 mi

    1. Drive from Des Plaines to Charlottecar car 746.2 mi
    13h 52m
    $137–197

  5. Fly Chicago O'Hare International Airport to Charlotte Douglas International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    3h 54m
    $123–413

  6. Fly Chicago O'Hare International Airport to Wilmington International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Wilmington International Airport (ILM)plane plane ORD - ILM
    3h 38m
    $94–427

  7. Fly Chicago O'Hare International Airport to Raleigh-Durham International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane plane ORD - RDU
    4h 39m
    $173–753

  8. Train, subway to Chicago Midway International Airport, fly to Charlotte Douglas International Airport

    1. Take the train from Des Plaines to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    5h 16m
    $129–713

  9. Train, subway to Chicago Midway International Airport, fly to Raleigh-Durham International Airport, line 100 bus

    1. Take the train from Des Plaines to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    4. Take the bus from RDU Airport at Terminal 2 to Hillsborough St at Enterprise Stbus bus
    5h 55m
    $159–313

  10. Bus

    1. Take the bus from Chicago Union Station to Toledobus bus Amtrak Thruway Connecting Service
    2. Take the bus from Toledo Bus Stop to Charlotte Bus Stationbus bus Greyhound US0140
    22h 31m
    $180–316

Des Plaines to North Carolina by train and bus

Calendar7Weekly Services
Duration21h 24mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Des Plaines to North Carolina.ExpandLaunch map view
  • Distance: 602.7 mi
  • Duration: 3h 25m

What companies run services between Des Plaines, IL, USA and North Carolina, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a train from Des Plaines to Charlotte Bus Station via Chicago OTC, Madison & Canal, Harrison & Jefferson, Chicago, Columbus - Mound St, and Hurricane in around 21h 24m.

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