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How to get fromDes Plaines to Ohioby plane, bus (Flixbus), train, bus, car, or subway

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There are 9 ways to get from Des Plaines to Ohio by plane, bus (Flixbus), train, bus, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Cleveland-Hopkins International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Cleveland-Hopkins International Airport (CLE)plane plane ORD - CLE
    3h 13m
    $373–803

  2. Drive 327.2 mi

    cheapest
    1. Drive from Des Plaines to Columbuscar car 327.2 mi
    6h 41m
    $60–87

  3. Bus (Flixbus)

    1. Take the bus from Chicago Bus Station to Columbusbus bus FlixBus 2511 / ...
    9h 9m
    $62–103

  4. Train, bus

    1. Take the train from Chicago Union Station to Toledotrain train Floridian / ...
    2. Take the bus from Toledo to Columbus - Mound Stbus bus Detroit
    9h 32m
    $104–213

  5. Fly Chicago O'Hare International Airport to John Glenn Columbus International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to John Glenn Columbus International Airport (CMH)plane plane ORD - CMH
    3h 43m
    $552–903

  6. Fly Chicago O'Hare International Airport to Dayton

    1. Fly from Chicago O'Hare International Airport (ORD) to Dayton (DAY)plane plane ORD - DAY
    4h 6m
    $112–752

  7. Fly Chicago O'Hare International Airport to Covington, line 46 bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Covington (CVG)plane plane ORD - CVG
    2. Take the bus from Government Square Area H to Vine St & McMillan St Northboundbus bus
    4h 4m
    $153–805

  8. Train, subway to Chicago Midway International Airport, fly to Cleveland-Hopkins International Airport

    1. Take the train from Des Plaines to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Cleveland-Hopkins International Airport (CLE)plane plane MDW - CLE
    4h 24m
    $94–563

  9. Train, subway to Chicago Midway International Airport, fly to John Glenn Columbus International Airport

    1. Take the train from Des Plaines to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to John Glenn Columbus International Airport (CMH)plane plane MDW - CMH
    4h 52m
    $93–563

Des Plaines to Ohio by train and bus (Flixbus)

Calendar16Weekly Services
Duration9h 9mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from Des Plaines to Ohio.ExpandLaunch map view
  • Distance: 329.8 mi
  • Duration: 3h 13m

What companies run services between Des Plaines, IL, USA and Ohio, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, Flixbus USA operates a bus from Chicago Bus Station to Columbus twice daily. Tickets cost $55–95 and the journey takes 7h 20m.

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