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How to get fromDes Plaines to Saint Paulby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or subway

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There are 7 ways to get from Des Plaines to Saint Paul by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    3h 19m
    $222–453

  2. Drive 381.9 mi

    cheapest
    1. Drive from Des Plaines to Saint Paulcar car 381.9 mi
    6h 15m
    $70–101

  3. Bus

    1. Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Stationbus bus Wisconsin Coach Lines
    2. Take the bus from Milwaukee Intermodal Station to Saint Paul Union Depotbus bus Greyhound US0150
    8h 15m
    $88–141

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train Borealis / ...
    9h 14m
    $137–278

  5. Bus to General Mitchell International Airport, fly

    1. Take the bus from Multi-Modal/Rental Car Facility to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Minneapolis–Saint Paul International Airport (MSP)plane plane MKE - MSP
    4h 18m
    $637–1,041

  6. Train, subway to Chicago Midway International Airport, fly

    1. Take the train from Des Plaines to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane plane MDW - MSP
    4h 46m
    $83–493

  7. Bus via Madison

    1. Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus bus Van Galder
    2. Take the bus from Madison to Minneapolisbus bus Jefferson Lines 966 / ...
    12h 8m
    $87–154

Des Plaines to Saint Paul by bus

Calendar49Weekly Buses
Duration8h 15mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

Map of how to get from Des Plaines to Saint Paul.ExpandLaunch map view
  • Distance: 344.1 mi
  • Duration: 3h 19m

What companies run services between Des Plaines, IL, USA and Saint Paul, MN, USA?

American Airlines, Delta, and two other airlines fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP) hourly. Alternatively, you can take a bus from Multi-Modal/Rental Car Facility to Saint Paul Union Depot via Milwaukee Intermodal Station in around 8h 15m.

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