There are 5 ways to get from Dessau to Prague by train, bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus via Dresden
best- Take the train from Dessau Hbf to Dresden Hauptbahnhoftrain 56
- Take the bus from Dresden Bayrische Strasse to Prague Florenc Central Bus Stationbus : Berlin Central Bus Station - Berlin Südkreuz Train Station / ...
4h 45mKč 954–2,090Train, bus
cheapest- Take the train from Dessau Hbf to Leipzig Hbftrain S2 / ...
- Take the bus from Leipzig central train station to Praha, ÚAN Florencbus N67 / ...
5h 33mKč 748–1,909Train
- Take the train from Dessau Hbf to Leipzig Hbftrain S2
- Take the train from Leipzig Hbf to Dresden Bahnhof Neustadttrain 55 / ...
- Take the train from Dresden-Neustadt to Praha-Holešovicetrain Rj
5h 30mKč 1,090–3,671Train, night train
- Take the train from Dessau Hbf to Leipzig Messetrain S2 / ...
- Take the nighttrain from Leipzig Messe to Praha Hlavni Nadrazinighttrain En
5h 34mKč 1,744–3,495Drive 308.9 km
- Drive from Dessau to Praguecar 308.9 km
2h 54mKč 1,194–1,724
Dessau to Prague by train and bus
Comparing Your Travel Options
The cheapest way to get from Dessau to Prague is to train and bus which costs 750 Kč - 2 000 Kč and takes 5h 33m.
The fastest way to get from Dessau to Prague is to drive which takes 2h 54m and costs 1 100 Kč - 1 800 Kč.
No, there is no direct train from Dessau to Prague. However, there are services departing from Dessau Hbf and arriving at Praha-Holešovice via Leipzig Hbf and Dresden-Neustadt. The journey, including transfers, takes approximately 5h 30m.
The distance between Dessau and Prague is 321 km. The road distance is 308.9 km.
The best way to get from Dessau to Prague without a car is to train and bus via Dresden which takes 4h 45m and costs 950 Kč - 2 100 Kč.
It takes approximately 4h 45m to get from Dessau to Prague, including transfers.
Dessau to Prague train services, operated by Deutsche Bahn Regio (DB Regional), depart from Dessau Hbf station.
Dessau to Prague train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Leipzig Hbf station.
Yes, the driving distance between Dessau to Prague is 309 km. It takes approximately 2h 54m to drive from Dessau to Prague.
Book your Dessau to Prague train tickets online with Omio.
What companies run services between Dessau, Germany and Prague, Czechia?
You can take a train from Dessau Hbf to Praha-Holešovice via Leipzig Hbf, Dresden Bahnhof Neustadt, and Dresden-Neustadt in around 5h 30m.
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Dessau Hbf to Dresden Hauptbahnhof
- Ave. Duration
- 1h 50m
- Frequency
- Once a week
- Estimated price
- Kč 700–1,700
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Dessau Hbf to Leipzig Hbf
- Ave. Duration
- 32 min
- Frequency
- Twice a week
- Estimated price
- Kč 240–550
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Leipzig Hbf to Dresden Bahnhof Neustadt
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- Kč 480–1,100
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Dessau Hbf to Leipzig Hbf
- Ave. Duration
- 32 min
- Frequency
- Twice a week
- Estimated price
- Kč 240–550
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Dessau Hbf to Leipzig Hbf
- Ave. Duration
- 57 min
- Frequency
- Every 30 minutes
- Estimated price
- Kč 270–1,200
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Leipzig Hbf to Dresden Bahnhof Neustadt
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- Kč 500–2,200
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Dessau Hbf to Leipzig Messe
- Ave. Duration
- 47 min
- Frequency
- Every 30 minutes
- Estimated price
- Kč 240–1,000
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Dessau Hbf to Leipzig Hbf
- Ave. Duration
- 57 min
- Frequency
- Every 30 minutes
- Estimated price
- Kč 270–1,200
- Website
- Deutsche Bahn Regio (DB Regional)
- Website
- LEO Express
Train from Leipzig Hbf to Dresden Bahnhof Neustadt
- Ave. Duration
- 1h 26m
- Frequency
- 5 times a week
- Schedules at
- LEO Express
- Phone
- +47 70 13 14 15
- [email protected]
- Website
- Danish Railways
Train from Dresden-Neustadt to Praha-Holešovice
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- Kč 362
- Website
- Danish Railways
- Phone
- _AUSTRIAN_RAILWAYS_(ÖBB)
- Website
- Austrian Railways
Night train from Leipzig Messe to Praha Hlavni Nadrazi
- Ave. Duration
- 3h 47m
- Frequency
- Twice a week
- Estimated price
- Kč 1,500–2,500
- Website
- Austrian Railways
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Dresden Bayrische Strasse to Prague Florenc Central Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- Kč 210–350
- Website
- RegioJet
- Phone
- +359 700 20 544
- Website
- Arda Tur
Bus from Dresden Bayrische Strasse to Prague Florenc Central Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- Kč 451
- Website
- Arda Tur
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Leipzig central train station to Praha, ÚAN Florenc
- Ave. Duration
- 3h 30m
- Frequency
- Every 4 hours
- Estimated price
- Kč 500–800
- Website
- Flixbus
Want to know more about travelling around Czechia
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
There are 4582+ hotels available in Prague.



























