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How to get fromDestin to Cape Girardeauby taxi, plane, bus, or car

Find Transport to Cape Girardeau

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There are 8 ways to get from Destin to Cape Girardeau by taxi, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Pensacola International Airport, fly to Cape Girardeau Municipal Airport

    best
    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Cape Girardeau Municipal Airport (CGI)plane plane PNS - CGI
    3h 15m
    $271–650

  2. Drive 608.2 mi

    cheapest
    1. Drive from Destin to Cape Girardeaucar car 608.2 mi
    11h 54m
    $111–161

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    5. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    20h 33m
    $341–507

  4. Fly Destin–Fort Walton Beach Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 8m
    $171–647

  5. Fly Destin–Fort Walton Beach Airport to Midamerica St. Louis Airport, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 29m
    $159–486

  6. Taxi to Northwest Florida Beaches International Airport, fly to Lambert–St. Louis International Airport, bus

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL)plane plane ECP - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 46m
    $275–770

  7. Taxi to Pensacola International Airport, fly to Lambert–St. Louis International Airport, bus

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane plane PNS - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 55m
    $241–669

  8. Taxi, bus via New South Memphis

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    5. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    23h 21m
    $276–451

Pensacola International Airport (PNS) to Cape Girardeau Municipal Airport (CGI) flights

Calendar2Weekly Planes
Duration1h 45mAverage Duration
Ticket$123Cheapest Price
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Questions & Answers

Map of how to get from Destin to Cape Girardeau.ExpandLaunch map view
  • Distance: 544.3 mi
  • Duration: 3h 15m

What companies run services between Destin, FL, USA and Cape Girardeau, MO, USA?

There is no direct connection from Destin to Cape Girardeau. However, you can take the taxi to Pensacola-Airport-PNS airport, fly to Cape Girardeau Municipal Airport (CGI), then take the taxi to Cape Girardeau. Alternatively, you can take the taxi to Crestview, take the bus to Tallahassee, walk to N Monroe Street and Silver Slipper Lane, take the bus to C.K. Steele Plaza Gate 22, take the bus to Nashville Bus Station, take the bus to Carbondale Intermodal Station, then take the taxi to Cape Girardeau.

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