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How to get fromDestin to Columbiaby plane, taxi, bus, or car

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There are 9 ways to get from Destin to Columbia by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Columbia Regional Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU)plane plane VPS - COU
    2h 41m
    $163–495

  2. Drive 849 mi

    cheapest
    1. Drive from Destin to Columbiacar car 849 mi
    15h 3m
    $155–224

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    5. Take the bus from St Louis Bus Station to Columbiabus bus
    26h 22m
    $272–447

  4. Fly Destin–Fort Walton Beach Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    2. Take the bus from St Louis Bus Station to Columbiabus bus
    6h 58m
    $162–648

  5. Taxi to Northwest Florida Beaches International Airport, fly to Lambert–St. Louis International Airport, bus

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL)plane plane ECP - STL
    3. Take the bus from St Louis Bus Station to Columbiabus bus
    7h 36m
    $271–771

  6. Taxi to Pensacola International Airport, fly to Lambert–St. Louis International Airport, bus

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane plane PNS - STL
    3. Take the bus from St Louis Bus Station to Columbiabus bus
    7h 45m
    $232–650

  7. Fly Destin–Fort Walton Beach Airport to Midamerica St. Louis Airport, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    2. Take the bus from St Louis Bus Station to Columbiabus bus
    7h 19m
    $155–487

  8. Fly Destin–Fort Walton Beach Airport to Kansas City, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Kansas City (MCI)plane plane VPS - MCI
    2. Take the bus from Kansas City Bus Station to Columbiabus bus
    7h 53m
    $182–740

  9. Taxi, bus via Atlanta

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    5. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    6. Take the bus from St Louis Bus Station to Columbiabus bus
    26h 58m
    $282–467

Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU) flights

Calendar2Weekly Planes
Duration1h 59mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Destin to Columbia.ExpandLaunch map view
  • Distance: 687.7 mi
  • Duration: 2h 41m

What companies run services between Destin, FL, USA and Columbia, MO, USA?

Allegiant Air flies from Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU) twice a week.

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